{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["86(2)"],"submitter":["Dong J"],"pubmed_abstract":["Vesicular disease caused by Seneca Valley virus (SVV) has recently emerged throughout China and caused certain industry losses. We used immunofluorescence and western blotting to confirm that 3 new SVV strains (CH-GDSG-2018-1, CH-GDSG-2018-2, and CH-GDSG-2018-3) were from 1 pig farm. Phylogenetic analysis revealed the following: i) all 3 strains belong to USA-GBI29-2015-like clades, ii) CH-GDSG-2018-3 might have diverged from CH-GDSG-2018-1 and CH-GDSG-2018-2, and iii) CH-GDSG-2018-3 is a recombinant of the CHhb17 and HeNKF-1 strains. Virus growth curves showed that CH-GDSG-2018-3 had stronger proliferation ability <i>in vitro</i>. Seneca Valley virus has evolved extensively within China and this study has furthered our understanding of SVV epidemiology."],"journal":["Canadian journal of veterinary research = Revue canadienne de recherche veterinaire"],"pagination":["102-107"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8978293"],"repository":["biostudies-literature"],"pubmed_title":["Evolutionary analysis of 3 isolates of Seneca Valley virus from a single pig farm."],"pmcid":["PMC8978293"],"pubmed_authors":["He S","Rao D","Geng X","Chen M","Dong J","Zhao P","Jiao F","Huang L","Chen B","Cong F"],"additional_accession":[]},"is_claimable":false,"name":"Evolutionary analysis of 3 isolates of Seneca Valley virus from a single pig farm.","description":"Vesicular disease caused by Seneca Valley virus (SVV) has recently emerged throughout China and caused certain industry losses. We used immunofluorescence and western blotting to confirm that 3 new SVV strains (CH-GDSG-2018-1, CH-GDSG-2018-2, and CH-GDSG-2018-3) were from 1 pig farm. Phylogenetic analysis revealed the following: i) all 3 strains belong to USA-GBI29-2015-like clades, ii) CH-GDSG-2018-3 might have diverged from CH-GDSG-2018-1 and CH-GDSG-2018-2, and iii) CH-GDSG-2018-3 is a recombinant of the CHhb17 and HeNKF-1 strains. Virus growth curves showed that CH-GDSG-2018-3 had stronger proliferation ability <i>in vitro</i>. Seneca Valley virus has evolved extensively within China and this study has furthered our understanding of SVV epidemiology.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-22T21:52:01.433Z","creation":"2025-02-19T01:27:44.613Z"},"accession":"S-EPMC8978293","cross_references":{"pubmed":["35388228"]}}