{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang L"],"funding":["National Natural Science Foundation of China","Natural Science Foundation of Guangdong Province"],"pagination":["509-516"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8978701"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(1)"],"pubmed_abstract":["In this paper, a system of tetracycline (TEC) degradation by the bio-cathode in a microbial fuel cell (MFC) was constructed. Overall, the co-metabolic degradation performance of TEC was studied through single factor experiments and the ecological risk was evaluated using the <i>E. coli</i> growth inhibition rate and resistance genes. High throughput sequencing (HTS) was utilized to profile the biofilm community structure of the bio-cathode. Results showed that the degradation rate of TEC reached greater than 90% under optimal conditions, which was 10 mg L<sup>-1</sup> initial TEC concentration, 0.2-0.7 g L<sup>-1</sup> sodium acetate concentration and 12-18 L h<sup>-1</sup> aeration. Furthermore, compared with the aerobic biodegradation of TEC, the degradation efficiency of the MFC bio-cathode for TEC was significantly increased by 50% and the eco-toxicity of TEC after 36 hour degradation was reduced by 60.9%, and TEC ARGs in effluent were cut down. HTS results showed that electrochemically active bacteria <i>Acetobacter</i> and TEC-resistant degradation bacteria <i>Hyphomicrobium</i>, <i>Clostridium</i> and <i>Rhodopseudomonas</i> were the main dominant bacteria in the cathode biofilm. Besides, based on 5 intermediates, degradation pathways involving deamidation, denitro dimethylation, dedimethylation and dehydroxylation of TEC were proposed. The degradation of TEC on the bio-cathode was mainly caused by microbial co-metabolism action. This study would enrich the study of MFC bio-cathodic degradation of antibiotics in water."],"journal":["RSC advances"],"pubmed_title":["Profiling of co-metabolic degradation of tetracycline by the bio-cathode in microbial fuel cells."],"pmcid":["PMC8978701"],"funding_grant_id":["2016B020240005","U1401235","21477039"],"pubmed_authors":["Liang D","Wang L","Shi Y"],"additional_accession":[]},"is_claimable":false,"name":"Profiling of co-metabolic degradation of tetracycline by the bio-cathode in microbial fuel cells.","description":"In this paper, a system of tetracycline (TEC) degradation by the bio-cathode in a microbial fuel cell (MFC) was constructed. Overall, the co-metabolic degradation performance of TEC was studied through single factor experiments and the ecological risk was evaluated using the <i>E. coli</i> growth inhibition rate and resistance genes. High throughput sequencing (HTS) was utilized to profile the biofilm community structure of the bio-cathode. Results showed that the degradation rate of TEC reached greater than 90% under optimal conditions, which was 10 mg L<sup>-1</sup> initial TEC concentration, 0.2-0.7 g L<sup>-1</sup> sodium acetate concentration and 12-18 L h<sup>-1</sup> aeration. Furthermore, compared with the aerobic biodegradation of TEC, the degradation efficiency of the MFC bio-cathode for TEC was significantly increased by 50% and the eco-toxicity of TEC after 36 hour degradation was reduced by 60.9%, and TEC ARGs in effluent were cut down. HTS results showed that electrochemically active bacteria <i>Acetobacter</i> and TEC-resistant degradation bacteria <i>Hyphomicrobium</i>, <i>Clostridium</i> and <i>Rhodopseudomonas</i> were the main dominant bacteria in the cathode biofilm. Besides, based on 5 intermediates, degradation pathways involving deamidation, denitro dimethylation, dedimethylation and dehydroxylation of TEC were proposed. The degradation of TEC on the bio-cathode was mainly caused by microbial co-metabolism action. This study would enrich the study of MFC bio-cathodic degradation of antibiotics in water.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-26T15:15:43.382Z","creation":"2025-04-06T14:53:47.603Z"},"accession":"S-EPMC8978701","cross_references":{"pubmed":["35424472"],"doi":["10.1039/d1ra07600k"]}}