biostudies-literatureDong YChengdu Normal University3783-3787https://www.ebi.ac.uk/biostudies/studies/S-EPMC8979275biostudies-literatureUnknown12(6)An atom-economical approach for the synthesis of arylquinones was achieved successfully <i>via</i> direct oxidative C-C dehydrogenative coupling reaction of quinones/hydroquinones with electron-rich arenes using an inexpensive Fe-I₂-(NH₄)₂S₂O₈ system. The efficiency of this catalytic approach was established with a broad scope of substrates involving quinones and hydroquinones to give high yields (60-89%) of several arylated quinones. The present protocol is simple, practical, and shows good functional group tolerance.RSC advancesIron catalyzed C-C dehydrogenative coupling reaction: synthesis of arylquinones from quinones/hydroquinones.PMC89792752021CS21ZCY02Dong YShen AChang BChen JWang ZFShi ZCHe BXie CLuo QQYang FfalseIron catalyzed C-C dehydrogenative coupling reaction: synthesis of arylquinones from quinones/hydroquinones.An atom-economical approach for the synthesis of arylquinones was achieved successfully <i>via</i> direct oxidative C-C dehydrogenative coupling reaction of quinones/hydroquinones with electron-rich arenes using an inexpensive Fe-I₂-(NH₄)₂S₂O₈ system. The efficiency of this catalytic approach was established with a broad scope of substrates involving quinones and hydroquinones to give high yields (60-89%) of several arylated quinones. The present protocol is simple, practical, and shows good functional group tolerance.2022-01-01T00:00:00Z2022 Jan2025-04-19T13:01:11.14Z2025-04-19T13:01:11.14ZS-EPMC89792753542536610.1039/d1ra08828a