{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Tan Y"],"pubmed_abstract":["<h4>Introduction</h4>Metabolic acidosis affects bone health. It remains unclear whether drinking natural mineral water is better for maintaining bone health in the youth with metabolic acidosis.<h4>Materials and methods</h4>Sixty young female rats (3-weeks-old) were randomly divided into three groups and drank purified water (PW, as control), bicarbonate-rich natural mineral water (Bic-NMW), or sulfate-rich natural mineral water (Sul-NMW), which, respectively, contained calcium (0.17, 155, and 175 mg/L), bicarbonate (0.1360, and 139 mg/L) and sulfate (0, 35.6, and 532 mg/L), for 16 weeks. In the last 3 weeks, metabolic acidosis was induced in 10 rats per group by adding NH<sub>4</sub>Cl (0.28 mM) to drinking water. The rats' blood, urine, and femur were collected for assessing acid-base st"],"journal":["Frontiers in nutrition"],"pagination":["813202"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8979287"],"repository":["biostudies-literature"],"pubmed_title":["Drinking Natural Mineral Water Maintains Bone Health in Young Rats With Metabolic Acidosis."],"pmcid":["PMC8979287"],"pubmed_authors":["Qiu Z","Jin H","Huang Y","Luo J","Shu W","Tan Y","Xu A","Zeng H","Wang Y","Xue J","Wang J","Wang L"],"additional_accession":[]},"is_claimable":false,"name":"Drinking Natural Mineral Water Maintains Bone Health in Young Rats With Metabolic Acidosis.","description":"<h4>Introduction</h4>Metabolic acidosis affects bone health. It remains unclear whether drinking natural mineral water is better for maintaining bone health in the youth with metabolic acidosis.<h4>Materials and methods</h4>Sixty young female rats (3-weeks-old) were randomly divided into three groups and drank purified water (PW, as control), bicarbonate-rich natural mineral water (Bic-NMW), or sulfate-rich natural mineral water (Sul-NMW), which, respectively, contained calcium (0.17, 155, and 175 mg/L), bicarbonate (0.1360, and 139 mg/L) and sulfate (0, 35.6, and 532 mg/L), for 16 weeks. In the last 3 weeks, metabolic acidosis was induced in 10 rats per group by adding NH<sub>4</sub>Cl (0.28 mM) to drinking water. The rats' blood, urine, and femur were collected for assessing acid-base st","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-05T15:52:45.733Z","creation":"2025-04-05T15:52:45.733Z"},"accession":"S-EPMC8979287","cross_references":{"pubmed":["35387196"],"doi":["10.3389/fnut.2022.813202"]}}