{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(4)"],"submitter":["Walecka-Kurczyk A"],"pubmed_abstract":["Here, we report a standardized method for the synthesis of <i>N</i>-protected (1-methoxyalkyl)amines by the electrochemical decarboxylative α-methoxylation of α-amino acid derivatives using the commercially available, easy-to-use, compact ElectraSyn 2.0 setup. The use of equipment with a standardized power source, electrodes, and other accessories allows this experimental procedure to be easily transferred to any laboratory in the world. A simple workup and chromatography-free purification produced the products in excellent yields above 90%."],"journal":["RSC advances"],"pagination":["2107-2114"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8979322"],"repository":["biostudies-literature"],"pubmed_title":["Non-Kolbe electrolysis of <i>N</i>-protected-α-amino acids: a standardized method for the synthesis of <i>N</i>-protected (1-methoxyalkyl)amines."],"pmcid":["PMC8979322"],"pubmed_authors":["Walecka-Kurczyk A","Walczak K","Michalak M","Pazdzierniok-Holewa A","Adamek J"],"additional_accession":[]},"is_claimable":false,"name":"Non-Kolbe electrolysis of <i>N</i>-protected-α-amino acids: a standardized method for the synthesis of <i>N</i>-protected (1-methoxyalkyl)amines.","description":"Here, we report a standardized method for the synthesis of <i>N</i>-protected (1-methoxyalkyl)amines by the electrochemical decarboxylative α-methoxylation of α-amino acid derivatives using the commercially available, easy-to-use, compact ElectraSyn 2.0 setup. The use of equipment with a standardized power source, electrodes, and other accessories allows this experimental procedure to be easily transferred to any laboratory in the world. A simple workup and chromatography-free purification produced the products in excellent yields above 90%.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-04T23:16:37.922Z","creation":"2025-04-04T23:16:37.922Z"},"accession":"S-EPMC8979322","cross_references":{"pubmed":["35425224"],"doi":["10.1039/d1ra08124a"]}}