{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lin C"],"funding":["Natural Science Foundation of Fujian Province","Fujian Medical University","National Natural Science Foundation of China","Joint Funds for the Innovation of Science and Technology of Fujian Province"],"pagination":["e340-e349"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8982379"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(4)"],"pubmed_abstract":["<h4>Background</h4>Nasopharyngeal carcinoma is an Epstein-Barr virus (EBV)-associated tumor that is highly common in southern China. Our previous sequencing data demonstrated that the EBV-encoded microRNA BART8-3p was most upregulated in nasopharyngeal carcinoma (NPC) and was closely associated with the metastasis of NPC. However, the values of plasma BART8-3p in NPC patients have not yet been well characterized.<h4>Material and methods</h4>We quantified plasma BART8-3p expression by quantitative real-time PCR in 205 newly diagnosed NPC patients. Kaplan-Meier analysis was used to compare overall survival (OS), distant metastasis-free survival (DMFS), and locoregional relapse-free survival (LRRFS) between the groups.<h4>Results</h4>Plasma pretreatment BART8-3p was highly expressed in NPC pa"],"journal":["The oncologist"],"pubmed_title":["Plasma Epstein-Barr Virus MicroRNA BART8-3p as a Diagnostic and Prognostic Biomarker in Nasopharyngeal Carcinoma."],"pmcid":["PMC8982379"],"funding_grant_id":["2020J05071","2019Y9037","81972717","2019QH1192"],"pubmed_authors":["Pan J","Lin C","Lin S","Lu T","Zong J","Lin K","Su Y","Zhang B","Guo Q","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"Plasma Epstein-Barr Virus MicroRNA BART8-3p as a Diagnostic and Prognostic Biomarker in Nasopharyngeal Carcinoma.","description":"<h4>Background</h4>Nasopharyngeal carcinoma is an Epstein-Barr virus (EBV)-associated tumor that is highly common in southern China. Our previous sequencing data demonstrated that the EBV-encoded microRNA BART8-3p was most upregulated in nasopharyngeal carcinoma (NPC) and was closely associated with the metastasis of NPC. However, the values of plasma BART8-3p in NPC patients have not yet been well characterized.<h4>Material and methods</h4>We quantified plasma BART8-3p expression by quantitative real-time PCR in 205 newly diagnosed NPC patients. Kaplan-Meier analysis was used to compare overall survival (OS), distant metastasis-free survival (DMFS), and locoregional relapse-free survival (LRRFS) between the groups.<h4>Results</h4>Plasma pretreatment BART8-3p was highly expressed in NPC pa","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-06-18T08:48:45.478Z","creation":"2025-04-19T21:48:17.318Z"},"accession":"S-EPMC8982379","cross_references":{"pubmed":["35380720"],"doi":["10.1093/oncolo/oyac024"]}}