biostudies-literatureLin CNatural Science Foundation of Fujian ProvinceFujian Medical UniversityNational Natural Science Foundation of ChinaJoint Funds for the Innovation of Science and Technology of Fujian Provincee340-e349https://www.ebi.ac.uk/biostudies/studies/S-EPMC8982379biostudies-literatureUnknown27(4)<h4>Background</h4>Nasopharyngeal carcinoma is an Epstein-Barr virus (EBV)-associated tumor that is highly common in southern China. Our previous sequencing data demonstrated that the EBV-encoded microRNA BART8-3p was most upregulated in nasopharyngeal carcinoma (NPC) and was closely associated with the metastasis of NPC. However, the values of plasma BART8-3p in NPC patients have not yet been well characterized.<h4>Material and methods</h4>We quantified plasma BART8-3p expression by quantitative real-time PCR in 205 newly diagnosed NPC patients. Kaplan-Meier analysis was used to compare overall survival (OS), distant metastasis-free survival (DMFS), and locoregional relapse-free survival (LRRFS) between the groups.<h4>Results</h4>Plasma pretreatment BART8-3p was highly expressed in NPC paThe oncologistPlasma Epstein-Barr Virus MicroRNA BART8-3p as a Diagnostic and Prognostic Biomarker in Nasopharyngeal Carcinoma.PMC89823792020J050712019Y9037819727172019QH1192Pan JLin CLin SLu TZong JLin KSu YZhang BGuo QXu YfalsePlasma Epstein-Barr Virus MicroRNA BART8-3p as a Diagnostic and Prognostic Biomarker in Nasopharyngeal Carcinoma.<h4>Background</h4>Nasopharyngeal carcinoma is an Epstein-Barr virus (EBV)-associated tumor that is highly common in southern China. Our previous sequencing data demonstrated that the EBV-encoded microRNA BART8-3p was most upregulated in nasopharyngeal carcinoma (NPC) and was closely associated with the metastasis of NPC. However, the values of plasma BART8-3p in NPC patients have not yet been well characterized.<h4>Material and methods</h4>We quantified plasma BART8-3p expression by quantitative real-time PCR in 205 newly diagnosed NPC patients. Kaplan-Meier analysis was used to compare overall survival (OS), distant metastasis-free survival (DMFS), and locoregional relapse-free survival (LRRFS) between the groups.<h4>Results</h4>Plasma pretreatment BART8-3p was highly expressed in NPC pa2022-01-01T00:00:00Z2022 Apr2026-06-18T08:48:45.478Z2025-04-19T21:48:17.318ZS-EPMC89823793538072010.1093/oncolo/oyac024