{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jin X"],"funding":["Southwest Medical University"],"pagination":["3998338"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8983225"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["2022"],"pubmed_abstract":["Simple, rapid, and accurate detection of myoinositol (MI) concentration in blood is crucial in diagnosing polycystic ovary syndrome, neurological disorders, and cancer. A novel electrochemical detection (IED) method was established to quantify MI in human serum using a disposable unmodified screen-printed carbon electrode (SPCE) for the first time. MI was detected indirectly by the reaction product of myoinositol dehydrogenase (IDH) and cofactor <i>β</i>-nicotinamide adenine dinucleotide (NAD<sup>+</sup>). Good linear calibration curves were obtained at the concentration range from 5.0 <i>μ</i>M to 500.0 <i>μ</i>M (<i>R</i> <sup>2</sup> = 0.9981) with the lower limits of detection (LOD) and quantification (LOQ) of 1.0 <i>μ</i>M and 2.5 <i>μ</i>M, respectively. Recoveries were calculated at"],"journal":["Journal of analytical methods in chemistry"],"pubmed_title":["Quantification of Myoinositol in Serum by Electrochemical Detection with an Unmodified Screen-Printed Carbon Electrode."],"pmcid":["PMC8983225"],"funding_grant_id":["2019YFS0332","2019YFH0010","19PJ293","2021ZKQN063"],"pubmed_authors":["Li G","Liu J","Jin X","Gu X","Tian G","Zhao Y","Kong X","Zhong M"],"additional_accession":[]},"is_claimable":false,"name":"Quantification of Myoinositol in Serum by Electrochemical Detection with an Unmodified Screen-Printed Carbon Electrode.","description":"Simple, rapid, and accurate detection of myoinositol (MI) concentration in blood is crucial in diagnosing polycystic ovary syndrome, neurological disorders, and cancer. A novel electrochemical detection (IED) method was established to quantify MI in human serum using a disposable unmodified screen-printed carbon electrode (SPCE) for the first time. MI was detected indirectly by the reaction product of myoinositol dehydrogenase (IDH) and cofactor <i>β</i>-nicotinamide adenine dinucleotide (NAD<sup>+</sup>). Good linear calibration curves were obtained at the concentration range from 5.0 <i>μ</i>M to 500.0 <i>μ</i>M (<i>R</i> <sup>2</sup> = 0.9981) with the lower limits of detection (LOD) and quantification (LOQ) of 1.0 <i>μ</i>M and 2.5 <i>μ</i>M, respectively. Recoveries were calculated at","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T12:57:42.083Z","creation":"2025-04-04T12:57:42.083Z"},"accession":"S-EPMC8983225","cross_references":{"pubmed":["35392281"],"doi":["10.1155/2022/3998338"]}}