biostudies-literatureUnknown9Baldassano SIt is estimated that one-third of the world's population lives in areas where iodine (I) is scarce and its deficiency is responsible for many related disorders, such as goiter, reproductive failure, hearing loss, growth impairment, congenital I deficiency syndrome, and numerous kinds of brain injury. Mineral deficiencies can be overcome <i>via</i> dietary diversification and mineral supplementation. An alternative or even complementary way is represented by the intake of biofortified foods, which can tackle this lack of micronutrients. In this short-term double-arm nutritional intervention study, a cohort of ten people was supplemented with curly endive leaf biofortified with I and ten people with curly endive without biofortification (Intervention Study on Iodine Biofortification VegetablFrontiers in nutrition871638https://www.ebi.ac.uk/biostudies/studies/S-EPMC8984677biostudies-literatureBiofortification: Effect of Iodine Fortified Food in the Healthy Population, Double-Arm Nutritional Study.PMC8984677Nuzzo DSabatino LDe Pasquale CDi Gaudio FCaldarella RPicone PBaldassano SDi Rosa LVasto SfalseBiofortification: Effect of Iodine Fortified Food in the Healthy Population, Double-Arm Nutritional Study.It is estimated that one-third of the world's population lives in areas where iodine (I) is scarce and its deficiency is responsible for many related disorders, such as goiter, reproductive failure, hearing loss, growth impairment, congenital I deficiency syndrome, and numerous kinds of brain injury. Mineral deficiencies can be overcome <i>via</i> dietary diversification and mineral supplementation. An alternative or even complementary way is represented by the intake of biofortified foods, which can tackle this lack of micronutrients. In this short-term double-arm nutritional intervention study, a cohort of ten people was supplemented with curly endive leaf biofortified with I and ten people with curly endive without biofortification (Intervention Study on Iodine Biofortification Vegetabl2022-01-01T00:00:00Z20222026-04-08T17:45:06.209Z2025-04-04T23:04:15.047ZS-EPMC89846773539965310.3389/fnut.2022.871638