biostudies-literatureNti ANNEI NIH HHS342-349https://www.ebi.ac.uk/biostudies/studies/S-EPMC8986568biostudies-literatureUnknown99(4)<h4>Significance</h4>The contrast sensitivity (CS) function provides a more detailed assessment of vision than visual acuity. It was found that center-distance multifocal contact lens designs that are increasingly being prescribed for myopia control reduce distance photopic and mesopic CS in nonpresbyopic patients across a range of spatial frequencies.<h4>Purpose</h4>This study aimed to determine the effect of center-distance multifocal soft contact lenses (MFCLs) on CS under photopic and mesopic conditions in nonpresbyopic patients.<h4>Methods</h4>Twenty-five myopic, nonpresbyopic adults were fitted binocularly with three lenses: Biofinity single vision contact lens (SVCL), Biofinity Multifocal D +2.50 add, and NaturalVue Multifocal in random order. Contrast sensitivity was measured at diOptometry and vision science : official publication of the American Academy of OptometryContrast Sensitivity with Center-distance Multifocal Soft Contact Lenses.PMC8986568P30 EY007551T35 EY007088Ritchey ERWolffsohn JSNti ANGregory HRBerntsen DAfalseContrast Sensitivity with Center-distance Multifocal Soft Contact Lenses.<h4>Significance</h4>The contrast sensitivity (CS) function provides a more detailed assessment of vision than visual acuity. It was found that center-distance multifocal contact lens designs that are increasingly being prescribed for myopia control reduce distance photopic and mesopic CS in nonpresbyopic patients across a range of spatial frequencies.<h4>Purpose</h4>This study aimed to determine the effect of center-distance multifocal soft contact lenses (MFCLs) on CS under photopic and mesopic conditions in nonpresbyopic patients.<h4>Methods</h4>Twenty-five myopic, nonpresbyopic adults were fitted binocularly with three lenses: Biofinity single vision contact lens (SVCL), Biofinity Multifocal D +2.50 add, and NaturalVue Multifocal in random order. Contrast sensitivity was measured at di2022-01-01T00:00:00Z2022 Apr2025-04-26T13:17:24.627Z2025-04-06T14:08:51.284ZS-EPMC89865683512171910.1097/opx.000000000000187410.1097/OPX.0000000000001874