biostudies-literatureUnknown16Salazar GNot only do glia form close associations with neurons throughout the central nervous system (CNS), but glial cells also interact closely with other glial cells. As these cells mature, they undergo a phenomenon known as glial tiling, where they grow to abut one another, often without invading each other's boundaries. Glial tiling occurs throughout the animal kingdom, from fruit flies to humans; however, not much is known about the glial-glial interactions that lead to and maintain this tiling. <i>Drosophila</i> provide a strong model to investigate glial-glial tiling, where tiling occurs both among individual glial cells of the same subtype, as well as between those of different subtypes. Furthermore, the spatial segregation of the CNS allows for the unique ability to visualize and manipulaFrontiers in cellular neuroscience826483https://www.ebi.ac.uk/biostudies/studies/S-EPMC8987577biostudies-literatureQuantifying Glial-Glial Tiling Using Automated Image Analysis in <i>Drosophila</i>.PMC8987577Salazar GMaserejian AECoutinho-Budd JRoss GfalseQuantifying Glial-Glial Tiling Using Automated Image Analysis in <i>Drosophila</i>.Not only do glia form close associations with neurons throughout the central nervous system (CNS), but glial cells also interact closely with other glial cells. As these cells mature, they undergo a phenomenon known as glial tiling, where they grow to abut one another, often without invading each other's boundaries. Glial tiling occurs throughout the animal kingdom, from fruit flies to humans; however, not much is known about the glial-glial interactions that lead to and maintain this tiling. <i>Drosophila</i> provide a strong model to investigate glial-glial tiling, where tiling occurs both among individual glial cells of the same subtype, as well as between those of different subtypes. Furthermore, the spatial segregation of the CNS allows for the unique ability to visualize and manipula2022-01-01T00:00:00Z20222025-04-19T12:55:04.013Z2025-04-19T12:55:04.013ZS-EPMC89875773540112110.3389/fncel.2022.826483