biostudies-literatureUnknown12Guha AImaging plays a vital role in the diagnosis, response assessment, and follow-up of patients with plasma cell bone disease. The radiologic diagnostic paradigm has thus far evolved with developing technology and availability of better imaging platforms; however, the skewed availability of these imaging modalities in developed vis-à-vis the developing countries along with the lack of uniformity in reporting has led to a consensus on the imaging criteria for diagnosing and response assessment in plasma cell dyscrasia. Therefore, it is imperative for not only the radiologists but also the treating oncologist to be aware of the criteria and appropriate imaging modality to be used in accordance with the clinical question. The review will allow the treating oncologist to answer the following questFrontiers in oncology825394https://www.ebi.ac.uk/biostudies/studies/S-EPMC8987930biostudies-literatureImaging for Plasma Cell Dyscrasias: What, When, and How?PMC8987930Guha AMahajan AKhattry NGoda JSAgarwal UShetty NVijan AfalseImaging for Plasma Cell Dyscrasias: What, When, and How?Imaging plays a vital role in the diagnosis, response assessment, and follow-up of patients with plasma cell bone disease. The radiologic diagnostic paradigm has thus far evolved with developing technology and availability of better imaging platforms; however, the skewed availability of these imaging modalities in developed vis-à-vis the developing countries along with the lack of uniformity in reporting has led to a consensus on the imaging criteria for diagnosing and response assessment in plasma cell dyscrasia. Therefore, it is imperative for not only the radiologists but also the treating oncologist to be aware of the criteria and appropriate imaging modality to be used in accordance with the clinical question. The review will allow the treating oncologist to answer the following quest2022-01-01T00:00:00Z20222025-04-04T19:10:27.509Z2025-04-04T19:10:27.509ZS-EPMC89879303540225310.3389/fonc.2022.825394