biostudies-literatureAllen TANIMH NIH HHS1014-1021https://www.ebi.ac.uk/biostudies/studies/S-EPMC8988096biostudies-literatureUnknown52(6)<h4>Background</h4>Individuals diagnosed with borderline personality disorder (BPD) often describe their lives as stressful and unpredictable. However, it is unclear whether the adversity faced by those with BPD is a product of stress reactivity or stress generation. Here, we examined the dynamic, prospective associations between BPD and stressful life events over 3 years. Given the heterogeneity present in BPD, we sought to understand which empirically derived dimensions of this heterogeneous disorder explain stress reactivity <i>v</i>. stress generation.<h4>Methods</h4>Participants included 355 individuals diagnosed with BPD and followed longitudinally at three annual assessments. Auto-regressive cross-lagged panel models were used to examine prospective associations between stressful liPsychological medicineBorderline personality disorder: stress reactivity or stress generation? A prospective dimensional study.PMC8988096T32 MH016804R01 MH119399R01 MH048463R01 MH100095Soloff PHAllen TAHallquist MNDombrovski AYfalseBorderline personality disorder: stress reactivity or stress generation? A prospective dimensional study.<h4>Background</h4>Individuals diagnosed with borderline personality disorder (BPD) often describe their lives as stressful and unpredictable. However, it is unclear whether the adversity faced by those with BPD is a product of stress reactivity or stress generation. Here, we examined the dynamic, prospective associations between BPD and stressful life events over 3 years. Given the heterogeneity present in BPD, we sought to understand which empirically derived dimensions of this heterogeneous disorder explain stress reactivity <i>v</i>. stress generation.<h4>Methods</h4>Participants included 355 individuals diagnosed with BPD and followed longitudinally at three annual assessments. Auto-regressive cross-lagged panel models were used to examine prospective associations between stressful li2022-01-01T00:00:00Z2022 Apr2025-04-19T08:18:25.496Z2025-02-19T04:22:18.154ZS-EPMC89880963271339810.1017/s003329172000255x10.1017/S003329172000255X