{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2022"],"submitter":["Liu Y"],"pubmed_abstract":["The traditional Chinese medicine <i>Gastrodia elata</i> (commonly called \"Tianma\" in Chinese) has been widely used in the treatment of rheumatism, epilepsy, paralysis, headache, and dizziness. Phenolic compounds, such as gastrodin, <i>para</i>-hydroxybenzyl alcohol (HBA), <i>p</i>-hydroxybenzaldehyde, and vanillin are the main bioactive components isolated from <i>Gastrodia elata</i>. These compounds not only are structurally related but also share similar pharmacological activities, such as antioxidative and anti-inflammatory activities, and effects on the treatment of aging-related diseases. Here, we investigated the effect of <i>para</i>-hydroxybenzyl alcohol (HBA) on neurodegenerative diseases and aging in models of <i>Caenorhabditis elegans</i> (<i>C. elegans</i>). Our results showed "],"journal":["Oxidative medicine and cellular longevity"],"pagination":["8986287"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8989581"],"repository":["biostudies-literature"],"pubmed_title":["<i>Para</i>-Hydroxybenzyl Alcohol Delays the Progression of Neurodegenerative Diseases in Models of <i>Caenorhabditis elegans</i> through Activating Multiple Cellular Protective Pathways."],"pmcid":["PMC8989581"],"pubmed_authors":["Luo HR","Liu Y","Wu GS","Shi L","Lu YY","Xiao HT","Zheng ZY","Huang L","Qu Y","Chen JN"],"additional_accession":[]},"is_claimable":false,"name":"<i>Para</i>-Hydroxybenzyl Alcohol Delays the Progression of Neurodegenerative Diseases in Models of <i>Caenorhabditis elegans</i> through Activating Multiple Cellular Protective Pathways.","description":"The traditional Chinese medicine <i>Gastrodia elata</i> (commonly called \"Tianma\" in Chinese) has been widely used in the treatment of rheumatism, epilepsy, paralysis, headache, and dizziness. Phenolic compounds, such as gastrodin, <i>para</i>-hydroxybenzyl alcohol (HBA), <i>p</i>-hydroxybenzaldehyde, and vanillin are the main bioactive components isolated from <i>Gastrodia elata</i>. These compounds not only are structurally related but also share similar pharmacological activities, such as antioxidative and anti-inflammatory activities, and effects on the treatment of aging-related diseases. Here, we investigated the effect of <i>para</i>-hydroxybenzyl alcohol (HBA) on neurodegenerative diseases and aging in models of <i>Caenorhabditis elegans</i> (<i>C. elegans</i>). Our results showed ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-19T21:49:28.799Z","creation":"2025-04-19T21:49:28.799Z"},"accession":"S-EPMC8989581","cross_references":{"pubmed":["35401930"],"doi":["10.1155/2022/8986287"]}}