{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2022"],"submitter":["Zhou L"],"pubmed_abstract":["<h4>Objective</h4>Although low-dose ketamine has been shown to be generally beneficial in terms of pain control in a variety of major surgery, there is no consensus regarding the effectiveness of supplemental ketamine analgesic use exclusively in spine surgery. The objective of this systematic review and meta-analysis of randomized controlled trials (RCTs) was to assess the efficacy and safety of perioperative low-dose ketamine for pain management and analgesic consumption in patients undergoing spine surgery.<h4>Methods</h4>A comprehensive literature search was performed for relevant studies using PubMed, EMBASE, Web of Science, and Cochrane Library. Patients who received perioperative low-dose ketamine were compared to the control group in terms of postoperative pain intensity, opioid co"],"journal":["Pain research & management"],"pagination":["1507097"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8989618"],"repository":["biostudies-literature"],"pubmed_title":["Perioperative Low-Dose Ketamine for Postoperative Pain Management in Spine Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials."],"pmcid":["PMC8989618"],"pubmed_authors":["Yang H","Zhou L","Hai Y","Cheng Y"],"additional_accession":[]},"is_claimable":false,"name":"Perioperative Low-Dose Ketamine for Postoperative Pain Management in Spine Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","description":"<h4>Objective</h4>Although low-dose ketamine has been shown to be generally beneficial in terms of pain control in a variety of major surgery, there is no consensus regarding the effectiveness of supplemental ketamine analgesic use exclusively in spine surgery. The objective of this systematic review and meta-analysis of randomized controlled trials (RCTs) was to assess the efficacy and safety of perioperative low-dose ketamine for pain management and analgesic consumption in patients undergoing spine surgery.<h4>Methods</h4>A comprehensive literature search was performed for relevant studies using PubMed, EMBASE, Web of Science, and Cochrane Library. Patients who received perioperative low-dose ketamine were compared to the control group in terms of postoperative pain intensity, opioid co","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T19:10:28.409Z","creation":"2025-04-04T19:10:28.409Z"},"accession":"S-EPMC8989618","cross_references":{"pubmed":["35401887"],"doi":["10.1155/2022/1507097"]}}