{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Tano S"],"pubmed_abstract":["<h4>Introduction</h4>Weight change during the interpregnancy is related to gestational diabetes mellitus (GDM) in the subsequent pregnancy. In interpregnancy care/counseling, the timeframe for goal setting is important, while the timing of the next conception is unpredictable and preventing age-related body weight gain is difficult. This study aimed to investigate the association between annual weight gain during the interpregnancy, which provide clearer timeframe, and GDM in subsequent pregnancies.<h4>Methods</h4>This multicenter retrospective study was conducted by collecting data on two pregnancies of the same women in 2009-2019. The association between annual BMI gain and GDM during the subsequent pregnancy was examined.<h4>Results</h4>This study included 1,640 pregnant women. A history of GDM [adjusted odds ratio (aOR), 26.22; 95% confidence interval (CI), 14.93-46.07] and annual BMI gain (aOR, 1.48; 95% CI, 1.22-1.81) were related to GDM during the subsequent pregnancy. In the women with a pre-pregnant BMI of <25.0 kg/m<sup>2</sup> and without GDM during the index pregnancy, an annual BMI gain of ≥0.6 kg/m<sup>2</sup>/year during the interpregnancy were associated with GDM in subsequent pregnancies; however, in the other subgroups, it was not associated with GDM in subsequent pregnancies.<h4>Conclusions</h4>For women with a pre-pregnant BMI of <25.0 kg/m<sup>2</sup> and without GDM during the index pregnancy, maintaining an annual BMI gain of <0.6 kg/m<sup>2</sup>/year may prevent GDM during the subsequent pregnancy."],"journal":["Frontiers in endocrinology"],"pagination":["815390"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8990746"],"repository":["biostudies-literature"],"pubmed_title":["Annual Body Mass Index Gain and Risk of Gestational Diabetes Mellitus in a Subsequent Pregnancy."],"pmcid":["PMC8990746"],"pubmed_authors":["Tano S","Nakano-Kobayashi T","Iitani Y","Kinoshita F","Yoshida S","Oguchi H","Kotani T","Imai K","Ushida T","Moriyama Y","Kishigami Y","Yoshihara M","Kajiyama H","Yamashita M"],"additional_accession":[]},"is_claimable":false,"name":"Annual Body Mass Index Gain and Risk of Gestational Diabetes Mellitus in a Subsequent Pregnancy.","description":"<h4>Introduction</h4>Weight change during the interpregnancy is related to gestational diabetes mellitus (GDM) in the subsequent pregnancy. In interpregnancy care/counseling, the timeframe for goal setting is important, while the timing of the next conception is unpredictable and preventing age-related body weight gain is difficult. This study aimed to investigate the association between annual weight gain during the interpregnancy, which provide clearer timeframe, and GDM in subsequent pregnancies.<h4>Methods</h4>This multicenter retrospective study was conducted by collecting data on two pregnancies of the same women in 2009-2019. The association between annual BMI gain and GDM during the subsequent pregnancy was examined.<h4>Results</h4>This study included 1,640 pregnant women. A history of GDM [adjusted odds ratio (aOR), 26.22; 95% confidence interval (CI), 14.93-46.07] and annual BMI gain (aOR, 1.48; 95% CI, 1.22-1.81) were related to GDM during the subsequent pregnancy. In the women with a pre-pregnant BMI of <25.0 kg/m<sup>2</sup> and without GDM during the index pregnancy, an annual BMI gain of ≥0.6 kg/m<sup>2</sup>/year during the interpregnancy were associated with GDM in subsequent pregnancies; however, in the other subgroups, it was not associated with GDM in subsequent pregnancies.<h4>Conclusions</h4>For women with a pre-pregnant BMI of <25.0 kg/m<sup>2</sup> and without GDM during the index pregnancy, maintaining an annual BMI gain of <0.6 kg/m<sup>2</sup>/year may prevent GDM during the subsequent pregnancy.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-05T14:43:07.982Z","creation":"2025-04-05T14:43:07.982Z"},"accession":"S-EPMC8990746","cross_references":{"pubmed":["35399932"],"doi":["10.3389/fendo.2022.815390"]}}