{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sasan S"],"funding":["Academy of Scientific and Innovative Research","University of Jammu","Council for Scientific and Industrial Research"],"pagination":["11114-11125"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8991908"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(13)"],"pubmed_abstract":["Two cyanoimidazopyridine-based sensors (SS1 and SS2) were explored for the colorimetric and fluorometric detection of Fe<sup>2+</sup>, Fe<sup>3+</sup>, and Cu<sup>2+</sup> ions in the semi-aqueous medium. The \"turn-off\" fluorescence response of both sensors to these ions was due to the restriction in internal charge transfer. Job's plot and semi-empirical calculations revealed that SS1 and SS2 complexed with Cu<sup>2+</sup> ions in a 1:1 ratio and Fe<sup>2+/3+</sup> ions in a 2:1 ratio, respectively. The sensors were found to have high binding constant (<i>K</i> <sub>a</sub>) values and low detection limit values. FMO analysis using the semi-empirical quantum mechanics method revealed the decrease in energy gap after complexation with metal ions. Sensor-coated filter paper strips were prepared and analyzed, where the color changes in the strips could be utilized for the real-time detection of Fe<sup>2+</sup>, Fe<sup>3+</sup>, and Cu<sup>2+</sup> ions."],"journal":["ACS omega"],"pubmed_title":["Fluorescence \"Turn-Off\" and Colorimetric Sensor for Fe<sup>2+</sup>, Fe<sup>3+</sup>, and Cu<sup>2+</sup> Ions Based on a 2,5,7-Triarylimidazopyridine Scaffold."],"pmcid":["PMC8991908"],"funding_grant_id":["OLP0136"],"pubmed_authors":["Gupta A","Parkesh R","Sasan S","Chopra T","Kapoor KK","Tsering D"],"additional_accession":[]},"is_claimable":false,"name":"Fluorescence \"Turn-Off\" and Colorimetric Sensor for Fe<sup>2+</sup>, Fe<sup>3+</sup>, and Cu<sup>2+</sup> Ions Based on a 2,5,7-Triarylimidazopyridine Scaffold.","description":"Two cyanoimidazopyridine-based sensors (SS1 and SS2) were explored for the colorimetric and fluorometric detection of Fe<sup>2+</sup>, Fe<sup>3+</sup>, and Cu<sup>2+</sup> ions in the semi-aqueous medium. The \"turn-off\" fluorescence response of both sensors to these ions was due to the restriction in internal charge transfer. Job's plot and semi-empirical calculations revealed that SS1 and SS2 complexed with Cu<sup>2+</sup> ions in a 1:1 ratio and Fe<sup>2+/3+</sup> ions in a 2:1 ratio, respectively. The sensors were found to have high binding constant (<i>K</i> <sub>a</sub>) values and low detection limit values. FMO analysis using the semi-empirical quantum mechanics method revealed the decrease in energy gap after complexation with metal ions. Sensor-coated filter paper strips were prepared and analyzed, where the color changes in the strips could be utilized for the real-time detection of Fe<sup>2+</sup>, Fe<sup>3+</sup>, and Cu<sup>2+</sup> ions.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-04T12:40:43.353Z","creation":"2025-04-04T12:40:43.353Z"},"accession":"S-EPMC8991908","cross_references":{"pubmed":["35415353"],"doi":["10.1021/acsomega.1c07193"]}}