biostudies-literatureStocker JKDutch Research Council (NWO)1476-1486https://www.ebi.ac.uk/biostudies/studies/S-EPMC8996778biostudies-literatureUnknown61(4)<h4>Objective</h4>SSc is a complex CTD affecting mental and physical health. Fatigue, hand function loss, and RP are the most prevalent disease-specific symptoms of systemic sclerosis. This study aimed to develop consensus and evidence-based recommendations for non-pharmacological treatment of these symptoms.<h4>Methods</h4>A multidisciplinary task force was installed comprising 20 Dutch experts. After agreeing on the method for formulating the recommendations, clinically relevant questions about patient education and treatments were inventoried. During a face-to-face task force meeting, draft recommendations were generated through a systematically structured discussion, following the nominal group technique. To support the recommendations, an extensive literature search was conducted in MRheumatology (Oxford, England)Evidence and consensus-based recommendations for non-pharmacological treatment of fatigue, hand function loss, Raynaud's phenomenon and digital ulcers in patients with systemic sclerosis.PMC8996778023.006.043Vonk MCvan den Hoogen FHJPotjewijd JNijhuis-van der Sanden MWGvan den Ende CHMStocker JKde Pundert LSchriemer MRStaal JBArthritis Research and Collaboration Hub study groupSchouffoer AASpierings JSatink TfalseEvidence and consensus-based recommendations for non-pharmacological treatment of fatigue, hand function loss, Raynaud's phenomenon and digital ulcers in patients with systemic sclerosis.<h4>Objective</h4>SSc is a complex CTD affecting mental and physical health. Fatigue, hand function loss, and RP are the most prevalent disease-specific symptoms of systemic sclerosis. This study aimed to develop consensus and evidence-based recommendations for non-pharmacological treatment of these symptoms.<h4>Methods</h4>A multidisciplinary task force was installed comprising 20 Dutch experts. After agreeing on the method for formulating the recommendations, clinically relevant questions about patient education and treatments were inventoried. During a face-to-face task force meeting, draft recommendations were generated through a systematically structured discussion, following the nominal group technique. To support the recommendations, an extensive literature search was conducted in M2022-01-01T00:00:00Z2022 Apr2025-04-21T17:32:51.199Z2025-04-05T16:40:36.766ZS-EPMC89967783426072310.1093/rheumatology/keab537