{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["23(7)"],"submitter":["Wang Y"],"pubmed_abstract":["In monocarpic plants, stem cells are fated to die. However, the potential mechanism of stem cell death has remained elusive. Here, we reveal that the levels of two forms of reactive oxygen species (ROS), superoxide anion free radical (O2·-) and hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), show dynamic changes in the shoot apex during the plant life cycle of <i>Arabidopsis thaliana</i>. We found that the level of O2·- decreased and disappeared at four weeks after bolting (WAB), while H<sub>2</sub>O<sub>2</sub> appeared at 3 WAB and showed a burst at 5 WAB. The timing of dynamic changes in O2·- and H<sub>2</sub>O<sub>2</sub> was delayed for approximately three weeks in <i>clv3-2</i>, which has a longer lifespan. Moreover, exogenous application of H<sub>2</sub>O<sub>2</sub> inhibited the e"],"journal":["International journal of molecular sciences"],"pagination":["3864"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8998593"],"repository":["biostudies-literature"],"pubmed_title":["Dynamic Changes in Reactive Oxygen Species in the Shoot Apex Contribute to Stem Cell Death in <i>Arabidopsis thaliana</i>."],"pmcid":["PMC8998593"],"pubmed_authors":["Ito T","Shirakawa M","Wang Y"],"additional_accession":[]},"is_claimable":false,"name":"Dynamic Changes in Reactive Oxygen Species in the Shoot Apex Contribute to Stem Cell Death in <i>Arabidopsis thaliana</i>.","description":"In monocarpic plants, stem cells are fated to die. However, the potential mechanism of stem cell death has remained elusive. Here, we reveal that the levels of two forms of reactive oxygen species (ROS), superoxide anion free radical (O2·-) and hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), show dynamic changes in the shoot apex during the plant life cycle of <i>Arabidopsis thaliana</i>. We found that the level of O2·- decreased and disappeared at four weeks after bolting (WAB), while H<sub>2</sub>O<sub>2</sub> appeared at 3 WAB and showed a burst at 5 WAB. The timing of dynamic changes in O2·- and H<sub>2</sub>O<sub>2</sub> was delayed for approximately three weeks in <i>clv3-2</i>, which has a longer lifespan. Moreover, exogenous application of H<sub>2</sub>O<sub>2</sub> inhibited the e","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2026-04-08T09:55:04.808Z","creation":"2024-12-03T18:59:24.626Z"},"accession":"S-EPMC8998593","cross_references":{"pubmed":["35409227"],"doi":["10.3390/ijms23073864"]}}