{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Xiao H"],"funding":["Guangdong Basic and Applied Basic Research Foundation"],"pagination":["2700000"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9001072"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["2022"],"pubmed_abstract":["More and more attention has been paid to the use of traditional phytochemicals. Here, we first verified the therapeutic potential of a natural bioactive compound called Hinokitiol in myocardial ischemia reperfusion injury. Hinokitiol exerts cardioprotective effect through inhibition of GSK-3<i>β</i> and subsequent elimination of excessive autophagy, tuning autophagic activity in moderate extent for remedial profit in acute myocardial infarction and myocardial ischemia reperfusion injury. Overall, our study establishes Hinokitiol as a novel available interventional treatment for myocardial ischemia reperfusion injury."],"journal":["Oxidative medicine and cellular longevity"],"pubmed_title":["Hinokitiol Protects Cardiomyocyte from Oxidative Damage by Inhibiting GSK3<i>β</i>-Mediated Autophagy."],"pmcid":["PMC9001072"],"funding_grant_id":["2018A030313980"],"pubmed_authors":["Liang S","Cai Q","Liu J","Yang Z","Xiao H","Chen X","Jin L"],"additional_accession":[]},"is_claimable":false,"name":"Hinokitiol Protects Cardiomyocyte from Oxidative Damage by Inhibiting GSK3<i>β</i>-Mediated Autophagy.","description":"More and more attention has been paid to the use of traditional phytochemicals. Here, we first verified the therapeutic potential of a natural bioactive compound called Hinokitiol in myocardial ischemia reperfusion injury. Hinokitiol exerts cardioprotective effect through inhibition of GSK-3<i>β</i> and subsequent elimination of excessive autophagy, tuning autophagic activity in moderate extent for remedial profit in acute myocardial infarction and myocardial ischemia reperfusion injury. Overall, our study establishes Hinokitiol as a novel available interventional treatment for myocardial ischemia reperfusion injury.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-20T00:17:16.023Z","creation":"2025-02-19T01:53:31.607Z"},"accession":"S-EPMC9001072","cross_references":{"pubmed":["35419165"],"doi":["10.1155/2022/2700000"]}}