{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Pang X"],"pubmed_abstract":["The aims of this research are to elucidate whether serum retinol is associated with type 2 diabetes and to explore the underlying mechanisms of the association in a prospective cohort study. A total of 3,526 diabetes-free participants aged 40 years or older were enrolled at baseline in 2010-2012. Multivariable logistic regression was adopted to evaluate the associations of serum retinol and dietary vitamin A (VA) intake with type 2 diabetes. Mediation analyses were used to reveal potential mediators in their associations. After a mean follow-up of 5.3 years, 280 incident cases of type 2 diabetes occurred. Serum retinol was positively associated with the incidence of type 2 diabetes. The multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for type 2 diabetes from the"],"journal":["Frontiers in nutrition"],"pagination":["831950"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9002104"],"repository":["biostudies-literature"],"pubmed_title":["The Association and Mediating Biomarkers of Serum Retinol in Influencing the Development of Type 2 Diabetes: A Prospective Cohort Study in Middle-Aged and Elderly Population."],"pmcid":["PMC9002104"],"pubmed_authors":["Li H","Li Y","Guo X","Zhang Y","Wei C","Sun C","Pang X","Wang Y","Yang S"],"additional_accession":[]},"is_claimable":false,"name":"The Association and Mediating Biomarkers of Serum Retinol in Influencing the Development of Type 2 Diabetes: A Prospective Cohort Study in Middle-Aged and Elderly Population.","description":"The aims of this research are to elucidate whether serum retinol is associated with type 2 diabetes and to explore the underlying mechanisms of the association in a prospective cohort study. A total of 3,526 diabetes-free participants aged 40 years or older were enrolled at baseline in 2010-2012. Multivariable logistic regression was adopted to evaluate the associations of serum retinol and dietary vitamin A (VA) intake with type 2 diabetes. Mediation analyses were used to reveal potential mediators in their associations. After a mean follow-up of 5.3 years, 280 incident cases of type 2 diabetes occurred. Serum retinol was positively associated with the incidence of type 2 diabetes. The multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for type 2 diabetes from the","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-21T17:30:24.896Z","creation":"2025-04-05T16:40:23.229Z"},"accession":"S-EPMC9002104","cross_references":{"pubmed":["35425797"],"doi":["10.3389/fnut.2022.831950"]}}