{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Hwang IS"],"pubmed_abstract":["<i>Clavibacter michiganensis</i>, a Gram-positive plant-pathogenic bacterium, utilizes apoplastic effectors for disease development in host plants. Here, we determine the roles of Pat-1<sub>Cm</sub> (a putative serine protease) in pathogenicity and plant immunity. Pat-1<sub>Cm</sub> was found to be a genuine secreted protein, and the secreted mature form did not carry the first 33 amino acids predicted to be a signal peptide (SP). The <i>pat-1<sub>Cm</sub></i> mutant impaired to cause wilting, but still caused canker symptom in tomato. Moreover, this mutant failed to trigger the hypersensitive response (HR) in a nonhost <i>Nicotiana tabacum</i>. Among orthologs and paralogs of <i>pat-1<sub>Cm</sub></i> , only <i>chp-7<sub>Cs</sub></i> from <i>Clavibacter sepedonicus</i>, a potato pathogen,"],"journal":["Frontiers in plant science"],"pagination":["888290"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9006514"],"repository":["biostudies-literature"],"pubmed_title":["An Apoplastic Effector Pat-1<sub>Cm</sub> of the Gram-Positive Bacterium <i>Clavibacter michiganensis</i> Acts as Both a Pathogenicity Factor and an Immunity Elicitor in Plants."],"pmcid":["PMC9006514"],"pubmed_authors":["Sohn KH","Choi D","Hwang IS","Park IW","Oh EJ","Song E","Lee Y","Oh CS"],"additional_accession":[]},"is_claimable":false,"name":"An Apoplastic Effector Pat-1<sub>Cm</sub> of the Gram-Positive Bacterium <i>Clavibacter michiganensis</i> Acts as Both a Pathogenicity Factor and an Immunity Elicitor in Plants.","description":"<i>Clavibacter michiganensis</i>, a Gram-positive plant-pathogenic bacterium, utilizes apoplastic effectors for disease development in host plants. Here, we determine the roles of Pat-1<sub>Cm</sub> (a putative serine protease) in pathogenicity and plant immunity. Pat-1<sub>Cm</sub> was found to be a genuine secreted protein, and the secreted mature form did not carry the first 33 amino acids predicted to be a signal peptide (SP). The <i>pat-1<sub>Cm</sub></i> mutant impaired to cause wilting, but still caused canker symptom in tomato. Moreover, this mutant failed to trigger the hypersensitive response (HR) in a nonhost <i>Nicotiana tabacum</i>. Among orthologs and paralogs of <i>pat-1<sub>Cm</sub></i> , only <i>chp-7<sub>Cs</sub></i> from <i>Clavibacter sepedonicus</i>, a potato pathogen,","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-05-31T07:00:08.966Z","creation":"2025-02-19T01:55:29.234Z"},"accession":"S-EPMC9006514","cross_references":{"pubmed":["35432427"],"doi":["10.3389/fpls.2022.888290"]}}