{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10"],"submitter":["Loo EXL"],"pubmed_abstract":["<h4>Background</h4>Epidemiological studies suggest a link between eczema and attention deficit hyperactivity disorder (ADHD), but underlying mechanisms have not been examined.<h4>Objective</h4>We aim to investigate the association between eczema and subsequent ADHD symptoms in the Growing Up in Singapore Towards healthy Outcomes cohort and explore the role of pro-inflammatory cytokines and gut microbiome.<h4>Methods</h4>The modified International Study of Asthma and Allergies in Childhood questionnaire and Computerized Diagnostic Interview Schedule for Children Version IV were administered to assess reported eczema within the first 18 months and presence of ADHD symptoms at 54 months, respectively. Skin prick testing at 18 months, cytokines in maternal blood during pregnancy and cord blood"],"journal":["Frontiers in pediatrics"],"pagination":["837741"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9007142"],"repository":["biostudies-literature"],"pubmed_title":["Associations Between Eczema and Attention Deficit Hyperactivity Disorder Symptoms in Children."],"pmcid":["PMC9007142"],"pubmed_authors":["Ta LDH","Tay MJY","Broekman BFP","Chong YS","Lau HX","Tham EH","Yap QV","Yap FKP","Meaney MJ","Gluckman P","Tan KML","Lee BW","Ooi DSQ","Goh AEN","Loo EXL","Xu J","Eriksson JG","Van Bever H","Shek LP","Ong M","Kramer M","Karnani N","Tan KH","Chan YH","Teoh OH"],"additional_accession":[]},"is_claimable":false,"name":"Associations Between Eczema and Attention Deficit Hyperactivity Disorder Symptoms in Children.","description":"<h4>Background</h4>Epidemiological studies suggest a link between eczema and attention deficit hyperactivity disorder (ADHD), but underlying mechanisms have not been examined.<h4>Objective</h4>We aim to investigate the association between eczema and subsequent ADHD symptoms in the Growing Up in Singapore Towards healthy Outcomes cohort and explore the role of pro-inflammatory cytokines and gut microbiome.<h4>Methods</h4>The modified International Study of Asthma and Allergies in Childhood questionnaire and Computerized Diagnostic Interview Schedule for Children Version IV were administered to assess reported eczema within the first 18 months and presence of ADHD symptoms at 54 months, respectively. Skin prick testing at 18 months, cytokines in maternal blood during pregnancy and cord blood","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-05-31T21:56:23.888Z","creation":"2025-04-04T19:30:09.585Z"},"accession":"S-EPMC9007142","cross_references":{"pubmed":["35433544"],"doi":["10.3389/fped.2022.837741"]}}