{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Tian B"],"pubmed_abstract":["<i>Hericium erinaceus</i> polysaccharides (HEPs) have attracted widespread attention in regulating gut microbiota (GM). To investigate digestibility and fermentation of HEPs and their effects on GM composition, three polysaccharide fractions, namely, HEP-30, HEP-50, and HEP-70, were fractionally precipitated with 30%, 50%, and 70% ethanol concentrations (v/v) from hot water-soluble extracts of <i>Hericium erinaceus</i>, respectively. Three kinds of prepared HEPs were structurally characterized and simulated gastrointestinal digestion, and their effects on human fecal microbiota fermentations of male and female and short-chain fatty acid (SCFA) production <i>in vitro</i> were clarified. Under digestive conditions simulating saliva, stomach, and small intestine, HEPs were not significantly i"],"journal":["Frontiers in nutrition"],"pagination":["858585"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9008368"],"repository":["biostudies-literature"],"pubmed_title":["Digestive Characteristics of <i>Hericium erinaceus</i> Polysaccharides and Their Positive Effects on Fecal Microbiota of Male and Female Volunteers During <i>in vitro</i> Fermentation."],"pmcid":["PMC9008368"],"pubmed_authors":["Zou X","Pi X","Sun P","Yang K","Mao R","Tian B","Xu T","Geng Y","Zeng X","Huang L","Wu W"],"additional_accession":[]},"is_claimable":false,"name":"Digestive Characteristics of <i>Hericium erinaceus</i> Polysaccharides and Their Positive Effects on Fecal Microbiota of Male and Female Volunteers During <i>in vitro</i> Fermentation.","description":"<i>Hericium erinaceus</i> polysaccharides (HEPs) have attracted widespread attention in regulating gut microbiota (GM). To investigate digestibility and fermentation of HEPs and their effects on GM composition, three polysaccharide fractions, namely, HEP-30, HEP-50, and HEP-70, were fractionally precipitated with 30%, 50%, and 70% ethanol concentrations (v/v) from hot water-soluble extracts of <i>Hericium erinaceus</i>, respectively. Three kinds of prepared HEPs were structurally characterized and simulated gastrointestinal digestion, and their effects on human fecal microbiota fermentations of male and female and short-chain fatty acid (SCFA) production <i>in vitro</i> were clarified. Under digestive conditions simulating saliva, stomach, and small intestine, HEPs were not significantly i","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-05-29T01:07:56.269Z","creation":"2025-02-19T00:38:24.533Z"},"accession":"S-EPMC9008368","cross_references":{"pubmed":["35433782"],"doi":["10.3389/fnut.2022.858585"]}}