biostudies-literatureUnknownKhatib S<h4>Background</h4>Fatigue following acute viral illnesses is a major issue that complicates the clinical course of several epidemic and non-epidemic viral infections. There is a noticeably higher trend of patients with symptoms that persist after initial recovery from acute COVID-19. This study seeks to obtain more data about the prevalence of post-COVID-19 fatigue and the factors associated with higher fatigue frequency among patients who had COVID-19.<h4>Methods</h4>A single center cross-sectional study was performed between May 2021 and January 2022 at University Health, Kansas City, Missouri, USA. The Fatigue Assessment Scale (FAS) was utilized to measure post-COVID-19 fatigue. Descriptive and comparative statistics were used to describe clinical and sociodemographic features of patieIrish journal of medical sciencehttps://www.ebi.ac.uk/biostudies/studies/S-EPMC9013544biostudies-literaturePost-COVID-19 fatigue as a major health problem: a cross-sectional study from Missouri, USA.PMC9013544Khatib SMasoud AGomez RSivasankar SSabobeh TJohn SHabib AfalsePost-COVID-19 fatigue as a major health problem: a cross-sectional study from Missouri, USA.<h4>Background</h4>Fatigue following acute viral illnesses is a major issue that complicates the clinical course of several epidemic and non-epidemic viral infections. There is a noticeably higher trend of patients with symptoms that persist after initial recovery from acute COVID-19. This study seeks to obtain more data about the prevalence of post-COVID-19 fatigue and the factors associated with higher fatigue frequency among patients who had COVID-19.<h4>Methods</h4>A single center cross-sectional study was performed between May 2021 and January 2022 at University Health, Kansas City, Missouri, USA. The Fatigue Assessment Scale (FAS) was utilized to measure post-COVID-19 fatigue. Descriptive and comparative statistics were used to describe clinical and sociodemographic features of patie2022-01-01T00:00:00Z2022 Apr2025-04-04T20:36:47.098Z2025-02-19T03:41:48.596ZS-EPMC90135443543477210.1007/s11845-022-03011-z