{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(4)"],"submitter":["Hu G"],"pubmed_abstract":["<h4>Background</h4>Systemic inflammatory response (SIR) plays important roles in initiation, promotion and progression of tumor. However, the prognostic role of baseline circulating platelet-to-lymphocyte ratio (PLR) (known as a marker of SIR) in human initial stage Ⅳ gastric cancer (GC) remains controversial. Hence, we performed this meta-analysis to assess the value of it in prognosis prediction for these patients.<h4>Materials and methods</h4>We searched PubMed, Embase and EBSCO to identify the studies and computed extracted data with STATA 12.0.<h4>Results</h4>A total of 3025 patients with initial stage Ⅳ GC from 13 published studies were incorporated into this meta-analysis. We found that elevated baseline circulating PLR was significantly associated with decreased overall survival (O"],"journal":["PloS one"],"pagination":["e0265897"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9015147"],"repository":["biostudies-literature"],"pubmed_title":["Elevated baseline circulating platelet-to-lymphocyte ratio and survival in initial stage Ⅳ gastric cancer patients: A meta-analysis."],"pmcid":["PMC9015147"],"pubmed_authors":["Hu G","Wang S","Huang L"],"additional_accession":[]},"is_claimable":false,"name":"Elevated baseline circulating platelet-to-lymphocyte ratio and survival in initial stage Ⅳ gastric cancer patients: A meta-analysis.","description":"<h4>Background</h4>Systemic inflammatory response (SIR) plays important roles in initiation, promotion and progression of tumor. However, the prognostic role of baseline circulating platelet-to-lymphocyte ratio (PLR) (known as a marker of SIR) in human initial stage Ⅳ gastric cancer (GC) remains controversial. Hence, we performed this meta-analysis to assess the value of it in prognosis prediction for these patients.<h4>Materials and methods</h4>We searched PubMed, Embase and EBSCO to identify the studies and computed extracted data with STATA 12.0.<h4>Results</h4>A total of 3025 patients with initial stage Ⅳ GC from 13 published studies were incorporated into this meta-analysis. We found that elevated baseline circulating PLR was significantly associated with decreased overall survival (O","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T20:37:02.565Z","creation":"2025-04-04T20:37:02.565Z"},"accession":"S-EPMC9015147","cross_references":{"pubmed":["35436305"],"doi":["10.1371/journal.pone.0265897"]}}