biostudies-literatureUnknown13Nakajima S<h4>Background and objective</h4>Hypercoagulability is associated with increased risks of ischemic stroke and subsequent mortality in patients with active cancer. This study investigated the relationships between plasma D-dimer levels after stroke treatment and short-term outcomes in patients with cancer-associated stroke.<h4>Methods</h4>This retrospective, observational, multicenter study analyzed consecutive patients with cancer-associated ischemic stroke. Hypercoagulability was assessed by plasma D-dimer levels before and after stroke treatment. Short-term outcomes were assessed in terms of poor outcomes (a modified Rankin Scale score >3), cumulative rates of recurrent ischemic stroke, and mortality at 30 days after admission.<h4>Results</h4>Of 282 patients, 135 (47.9%) showed poor outcFrontiers in neurology868137https://www.ebi.ac.uk/biostudies/studies/S-EPMC9015657biostudies-literaturePost-Treatment Plasma D-Dimer Levels Are Associated With Short-Term Outcomes in Patients With Cancer-Associated Stroke.PMC9015657Hira KUeno YUrabe TKawano HFujimoto SMiyamoto NNakajima SKurita NYamashiro KKameda THirano TTanaka RWatanabe MHattori NfalsePost-Treatment Plasma D-Dimer Levels Are Associated With Short-Term Outcomes in Patients With Cancer-Associated Stroke.<h4>Background and objective</h4>Hypercoagulability is associated with increased risks of ischemic stroke and subsequent mortality in patients with active cancer. This study investigated the relationships between plasma D-dimer levels after stroke treatment and short-term outcomes in patients with cancer-associated stroke.<h4>Methods</h4>This retrospective, observational, multicenter study analyzed consecutive patients with cancer-associated ischemic stroke. Hypercoagulability was assessed by plasma D-dimer levels before and after stroke treatment. Short-term outcomes were assessed in terms of poor outcomes (a modified Rankin Scale score >3), cumulative rates of recurrent ischemic stroke, and mortality at 30 days after admission.<h4>Results</h4>Of 282 patients, 135 (47.9%) showed poor outc2022-01-01T00:00:00Z20222025-04-18T23:02:29.698Z2025-04-07T10:46:43.123ZS-EPMC90156573544461210.3389/fneur.2022.868137