{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["19(4)"],"submitter":["Lambert AM"],"funding":["NIHR Birmingham Biomedical Research Centre","National Institute for Health Research (NIHR)"],"pubmed_abstract":["<h4>Background</h4>Severe mental illness (SMI; schizophrenia, bipolar disorders (BDs), and other nonorganic psychoses) is associated with increased risk of cardiovascular disease (CVD) and CVD-related mortality. To date, no systematic review has investigated changes in population level CVD-related mortality over calendar time. It is unclear if this relationship has changed over time in higher-income countries with changing treatments.<h4>Methods and findings</h4>To address this gap, a systematic review was conducted, to assess the association between SMI and CVD including temporal change. Seven databases were searched (last: November 30, 2021) for cohort or case-control studies lasting ≥1 year, comparing frequency of CVD mortality or incidence in high-income countries between people with v"],"journal":["PLoS medicine"],"pagination":["e1003960"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9017899"],"repository":["biostudies-literature"],"pubmed_title":["Temporal trends in associations between severe mental illness and risk of cardiovascular disease: A systematic review and meta-analysis."],"pmcid":["PMC9017899"],"pubmed_authors":["Ryan R","Pearce E","Avsar TS","Price MJ","Odland ML","Ahmed K","Solmi M","Lee A","Parretti HM","Matthewman G","Correll CU","Tyldesley-Marshall N","Riley M","Marshall T","Lambert AM"],"additional_accession":[]},"is_claimable":false,"name":"Temporal trends in associations between severe mental illness and risk of cardiovascular disease: A systematic review and meta-analysis.","description":"<h4>Background</h4>Severe mental illness (SMI; schizophrenia, bipolar disorders (BDs), and other nonorganic psychoses) is associated with increased risk of cardiovascular disease (CVD) and CVD-related mortality. To date, no systematic review has investigated changes in population level CVD-related mortality over calendar time. It is unclear if this relationship has changed over time in higher-income countries with changing treatments.<h4>Methods and findings</h4>To address this gap, a systematic review was conducted, to assess the association between SMI and CVD including temporal change. Seven databases were searched (last: November 30, 2021) for cohort or case-control studies lasting ≥1 year, comparing frequency of CVD mortality or incidence in high-income countries between people with v","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-19T17:37:14.827Z","creation":"2025-04-19T17:37:14.827Z"},"accession":"S-EPMC9017899","cross_references":{"pubmed":["35439243"],"doi":["10.1371/journal.pmed.1003960"]}}