{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(16)"],"submitter":["Guo J"],"pubmed_abstract":["We report herein a novel approach involving optical resolution of (±)-1,16-dihydroxytetraphenylene (DHTP) by chiral gold(iii) complexation. This method features several key advantages, <i>i.e.</i>, recyclability of chiral resolution reagents, feasibility of scaling up to gram quantities, and operational simplicity. On the basis of this method, which led to optically pure DHTP, a library of 2,15-diaryl (<i>S</i>)-DHTPs and several (<i>S</i>)-DHTP-derived phosphoramidite ligands were synthesized. Finally, the superior performance of a (<i>S</i>)-DHTP phosphoramidite ligand was demonstrated by efficient iridium-catalyzed asymmetric allylic alkynylation reactions."],"journal":["Chemical science"],"pagination":["4608-4615"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9020179"],"repository":["biostudies-literature"],"pubmed_title":["Optical resolution of 1,16-dihydroxytetraphenylene by chiral gold(iii) complexation and its applications as chiral ligands in asymmetric catalysis."],"pmcid":["PMC9020179"],"pubmed_authors":["Cui JF","Guo J","Wong HNC","Zhou YY","Fan L","Xiong WB","Ma HR"],"additional_accession":[]},"is_claimable":false,"name":"Optical resolution of 1,16-dihydroxytetraphenylene by chiral gold(iii) complexation and its applications as chiral ligands in asymmetric catalysis.","description":"We report herein a novel approach involving optical resolution of (±)-1,16-dihydroxytetraphenylene (DHTP) by chiral gold(iii) complexation. This method features several key advantages, <i>i.e.</i>, recyclability of chiral resolution reagents, feasibility of scaling up to gram quantities, and operational simplicity. On the basis of this method, which led to optically pure DHTP, a library of 2,15-diaryl (<i>S</i>)-DHTPs and several (<i>S</i>)-DHTP-derived phosphoramidite ligands were synthesized. Finally, the superior performance of a (<i>S</i>)-DHTP phosphoramidite ligand was demonstrated by efficient iridium-catalyzed asymmetric allylic alkynylation reactions.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2024-12-04T04:14:08.047Z","creation":"2024-12-04T04:14:08.047Z"},"accession":"S-EPMC9020179","cross_references":{"pubmed":["35656141"],"doi":["10.1039/d2sc00388k"]}}