{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["28"],"submitter":["Hansen CH"],"funding":["Stein Erik Hagen Foundation for Clinical Heart Research"],"pubmed_abstract":["We examined whether resting levels and exercise-induced changes during exercise ECG stress test (EST) of cardiac Troponin T (cTnT), NT-proBNP and prothrombotic markers were affected by revascularization in patients with coronary artery disease (CAD).EST1 was performed before coronary angiography and revascularization, and patients (n  =  20) with confirmed CAD, performed another EST (EST2) 9 weeks later. Blood samples were drawn at rest and within five min after termination of ESTs.cTnT and NT-proBNP increased during exercise at both ESTs (p < 0.001, all). Resting cTnT levels at EST2 versus EST1 were significantly higher (p  =  0.02) whereas NT-proBNP did not differ. At both visits, increased D-dimer (p  =  0.008 and <0.001), pro-thrombin fragment 1  +  2 (p  =  0.009 and 0.001) and tissue"],"journal":["Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis"],"pagination":["10760296221094029"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9021467"],"repository":["biostudies-literature"],"pubmed_title":["Effect of Revascularization on Exercise-Induced Changes in Cardiac and Prothrombotic Biomarkers in Patients with Coronary Artery Disease."],"pmcid":["PMC9021467"],"pubmed_authors":["Hansen CH","Cwikiel J","Flaa A","Arnesen H","Seljeflot I","Bratseth V"],"additional_accession":[]},"is_claimable":false,"name":"Effect of Revascularization on Exercise-Induced Changes in Cardiac and Prothrombotic Biomarkers in Patients with Coronary Artery Disease.","description":"We examined whether resting levels and exercise-induced changes during exercise ECG stress test (EST) of cardiac Troponin T (cTnT), NT-proBNP and prothrombotic markers were affected by revascularization in patients with coronary artery disease (CAD).EST1 was performed before coronary angiography and revascularization, and patients (n  =  20) with confirmed CAD, performed another EST (EST2) 9 weeks later. Blood samples were drawn at rest and within five min after termination of ESTs.cTnT and NT-proBNP increased during exercise at both ESTs (p < 0.001, all). Resting cTnT levels at EST2 versus EST1 were significantly higher (p  =  0.02) whereas NT-proBNP did not differ. At both visits, increased D-dimer (p  =  0.008 and <0.001), pro-thrombin fragment 1  +  2 (p  =  0.009 and 0.001) and tissue","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan-Dec","modification":"2026-06-01T01:00:26.024Z","creation":"2024-10-17T20:03:24.256Z"},"accession":"S-EPMC9021467","cross_references":{"pubmed":["35437054"],"doi":["10.1177/10760296221094029"]}}