biostudies-literatureUnknown6(4)Nakano D(a) Summary for SGLT2i-induced alterations in 48 chemokines/cytokines in Hep3B and Huh7 cells. (b) SGLT2i-induced changes in the medium CXCL1 level (each <i>n</i> = 4). (c) SGLT2i-induced changes in the medium CXCL8 level (each <i>n</i> = 4). (d) SGLT2i-induced changes in the medium CXCL10 level (each <i>n</i> = 4), (e) SGLT2i-induced changes in the medium M-CSF level (each <i>n</i> = 4). The SGLT2i-induced significant changes in chemokines/cytokines are expressed as the percentage of control (the mean value of the control was set as 100%). CXCL, C-X-C motif chemokine ligand; G-CSF, granulocyte colony-stimulating factor; IL, interleukin; LIF, leukemia inhibitory factor; M-CSF, macrophage colony-stimulating factor; MIP-1α, macrophage inflammatory protein-1α; SDF-1α, stromal-cell-derived facJGH open : an open access journal of gastroenterology and hepatology270-273https://www.ebi.ac.uk/biostudies/studies/S-EPMC9021706biostudies-literatureEffects of SGLT2 inhibitor on tumor-releasing chemokines/cytokines in Hep3B and Huh7 cells.PMC9021706Yoshio SKoga HTorimura TTsutsumi TNakano DKawaguchi THayakawa MfalseEffects of SGLT2 inhibitor on tumor-releasing chemokines/cytokines in Hep3B and Huh7 cells.(a) Summary for SGLT2i-induced alterations in 48 chemokines/cytokines in Hep3B and Huh7 cells. (b) SGLT2i-induced changes in the medium CXCL1 level (each <i>n</i> = 4). (c) SGLT2i-induced changes in the medium CXCL8 level (each <i>n</i> = 4). (d) SGLT2i-induced changes in the medium CXCL10 level (each <i>n</i> = 4), (e) SGLT2i-induced changes in the medium M-CSF level (each <i>n</i> = 4). The SGLT2i-induced significant changes in chemokines/cytokines are expressed as the percentage of control (the mean value of the control was set as 100%). CXCL, C-X-C motif chemokine ligand; G-CSF, granulocyte colony-stimulating factor; IL, interleukin; LIF, leukemia inhibitory factor; M-CSF, macrophage colony-stimulating factor; MIP-1α, macrophage inflammatory protein-1α; SDF-1α, stromal-cell-derived fac2022-01-01T00:00:00Z2022 Apr2025-04-04T19:09:46.998Z2025-04-04T19:09:46.998ZS-EPMC90217063547520110.1002/jgh3.12730