{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Biswas S"],"funding":["Canadian Institutes of Health Research"],"pubmed_abstract":["With increasing incidence of diabetes worldwide, there is an ever-expanding number of patients with chronic diabetic complications such as diabetic retinopathy (DR), one of the leading causes of blindness in the working age population. Early screening for the onset and severity of DR is essential for timely intervention. With recent advancements in genomic technologies, epigenetic alterations in DR are beginning to unravel. Long non-coding RNAs (lncRNAs), which are key epigenetic mediators, have demonstrated implications in several (DR) related processes. Based on the previous research, we have developed a serum-based, multi-panel PCR test using 9 lncRNAs (<i>ANRIL</i>, <i>MALAT1</i>, <i>WISPER</i>, <i>ZFAS1</i>, <i>H19</i>, <i>HOTAIR</i>, <i>HULC</i>, <i>MEG3</i>, and <i>MIAT</i>) to iden"],"journal":["Frontiers in endocrinology"],"pagination":["851967"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9022211"],"repository":["biostudies-literature"],"pubmed_title":["Expressions of Serum lncRNAs in Diabetic Retinopathy - A Potential Diagnostic Tool."],"pmcid":["PMC9022211"],"pubmed_authors":["Coyle A","Gostimir M","Biswas S","Gonder J","Chen S","Chakrabarti S"],"additional_accession":[]},"is_claimable":false,"name":"Expressions of Serum lncRNAs in Diabetic Retinopathy - A Potential Diagnostic Tool.","description":"With increasing incidence of diabetes worldwide, there is an ever-expanding number of patients with chronic diabetic complications such as diabetic retinopathy (DR), one of the leading causes of blindness in the working age population. Early screening for the onset and severity of DR is essential for timely intervention. With recent advancements in genomic technologies, epigenetic alterations in DR are beginning to unravel. Long non-coding RNAs (lncRNAs), which are key epigenetic mediators, have demonstrated implications in several (DR) related processes. Based on the previous research, we have developed a serum-based, multi-panel PCR test using 9 lncRNAs (<i>ANRIL</i>, <i>MALAT1</i>, <i>WISPER</i>, <i>ZFAS1</i>, <i>H19</i>, <i>HOTAIR</i>, <i>HULC</i>, <i>MEG3</i>, and <i>MIAT</i>) to iden","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T12:43:21.568Z","creation":"2025-02-19T03:27:36.512Z"},"accession":"S-EPMC9022211","cross_references":{"pubmed":["35464068"],"doi":["10.3389/fendo.2022.851967"]}}