{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kimura S"],"funding":["British Heart Foundation"],"pagination":["1540-1549"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9022681"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["53(5)"],"pubmed_abstract":["<h4>Background</h4>The \"1-3-6-12-day rule\" for starting direct oral anticoagulants (DOACs) in patients with nonvalvular atrial fibrillation after acute ischemic stroke or transient ischemic attack recommends timings that may be later than used in clinical practice. We investigated more practical optimal timing of DOAC initiation according to stroke severity.<h4>Methods</h4>The combined data of prospective registries in Japan, Stroke Acute Management with Urgent Risk-factor Assessment and Improvement-nonvalvular atrial fibrillation (September 2011 to March 2014) and RELAXED (February 2014 to April 2016) were used. Patients were divided into transient ischemic attack and 3 stroke subgroups by the National Institutes of Health Stroke Scale score: mild (0-7), moderate (8-15), and severe (≥16)."],"journal":["Stroke"],"pubmed_title":["Practical \"1-2-3-4-Day\" Rule for Starting Direct Oral Anticoagulants After Ischemic Stroke With Atrial Fibrillation: Combined Hospital-Based Cohort Study."],"pmcid":["PMC9022681"],"funding_grant_id":["CS/17/6/33361"],"pubmed_authors":["Anwar I","Pallesen LP","Shiokawa Y","Chondrogianni M","Nallasivam A","Corea F","Kameda T","Kargiotis O","Datta P","Tassi R","Agnelli G","Kudo K","Acampa M","Stoll S","Inoue M","Gourbali V","Hert L","Furie KL","Mochizuki H","Yasaka M","Padovani A","Furukawa Y","Yagita Y","Makaritsis K","Colombo G","England T","Kallmunzer B","Del Sette M","Micheletti N","Gensicke H","Sasaki M","De Lodovici ML","Carletti M","Luder R","Polymeris A","Koga M","Mangion D","Schaub F","Hashimoto Y","Nagao T","Kitagawa K","Bandini F","Lees KR","Barlinn K","Dittrich T","Barlinn J","Shibuya S","Harrington F","Arihiro S","Rigatelli A","Emsley H","Chiti A","Csiba L","Sato S","Hamasaki T","Mohd Nor A","Sajid M","Nishiyama K","Uchiyama S","Letteri F","Sekaran L","Bellesini M","Cohen D","Manoj A","Putaala J","Furui E","Elmarimi A","Takagi M","Martini G","Davis M","Lotti EM","Masotti L","Venti M","Mumoli N","Chiba T","Werring DJ","Volbers B","Takamatsu K","Zedde M","Deleu D","Peters N","Sharma P","Wagner B","Szabo L","Okuda S","Wilkinson P","Siedler G","Shiozawa M","Anna Cimini L","Doronin B","Todo K","Corrigan J","Staals J","Nogawa S","Yamagami H","Roffe C","Sword J","Guideri F","Harkness K","Nagatsuka K","Avramiotis NS","Marsh R","Terayama Y","Giuntini M","Scott J","Giallombardo E","Dani K","Vanacker P","Parry-Jones A","Esis B","Yaghi S","Zivelonghi C","Alberti A","Pasco K","Bovi P","Smyth N","McCormich M","Mori E","Ispoglou S","Ntaios G","Chadha D","Ageno W","Ciccone A","Okwera J","Warburton E","Caso V","Guyler P","Tiseo C","Cappellari M","Macha K","Kario K","Tomppo L","Zietz A","Cooper M","Saastamoinen K","Melikyan G","Scoditti U","Lyrer PA","Bruce D","Andole S","Ulivi L","Hargroves D","Denti L","Patterson C","Pezzini A","Mansoor S","Hirano T","Akiyama H","Birns J","Sacco S","Burn M","Kamiyama K","Vahidassr D","Baronello MM","Ibrahim F","Hirai T","Flomin Y","Yoshimura S","Pieroni A","Meenakishundaram S","Schwab S","Tsivgoulis G","Rehman H","Mahawish K","Tomelleri G","Bonetti B","Galati F","Kimura S","Kimura T","Tassinari T","Krishnamurthy V","Kimura K","Athanasakis G","Sohn SI","Tatlisumak T","Flossman E","Tanaka K","Paciaroni M","Parry A","Tadi P","Shaw L","Tokunaga K","Acciarresi M","Karagkiozi E","Houkin K","Orlandi G","Putterill J","Bonati LH","Marcheselli S","Silvestrelli G","Leach S","De Marchis GM","Vannucchi V","Price C","Aghoram P","Volodina V","Gaßmann L","Terasaki T","Giorli E","Ito Y","Kobayashi S","Vadikolias K","SAMURAI, RELAXED, RAF, RAF-NOAC, CROMIS-2, NOACISP LONGTERM, Erlangen Registry and Verona Registry Investigators","Giannini N","Karapanayiotides T","Engelter ST","Wang R","Akhtar N","Holmes C","Yoshimoto T","Toni D","Becattini C","Toyoda K","Itabashi R","Tanahashi N","Abdul-Rahim AH","Hasegawa Y","Proschel H","Fladt J","Iveson L","D'Amore C","Kumon Y","Homma K","O'Connell J","Michel P","Sprigg N","Nakashima T","Sakamoto T","Meya L","Maccarrone M","Zabzuni D","Gunathilagan G","Mamun M","Thilemann S","Kee K","Rueckert C","Power M","Kitazono T","Lorenzini G","Liantinioti C","Bamford J","Baldi A","Yamaguchi T","Minematsu K","Choy L","Poli L","Monaco S","Veltkamp R","Haupenthal D","Mancuso M","Takizawa S","Matsuoka H","Nagata K","Fisch U","Okada Y","Smith M","Subramonian S","Traenka C","Nagakane Y","Lanari A","Imberti D","Giulia Mosconi M","O'Mahony P","Nakagawara J","Giustozzi M","Emiliani A","Matsumoto M","Manawadu D","Seiffge DJ"],"additional_accession":[]},"is_claimable":false,"name":"Practical \"1-2-3-4-Day\" Rule for Starting Direct Oral Anticoagulants After Ischemic Stroke With Atrial Fibrillation: Combined Hospital-Based Cohort Study.","description":"<h4>Background</h4>The \"1-3-6-12-day rule\" for starting direct oral anticoagulants (DOACs) in patients with nonvalvular atrial fibrillation after acute ischemic stroke or transient ischemic attack recommends timings that may be later than used in clinical practice. We investigated more practical optimal timing of DOAC initiation according to stroke severity.<h4>Methods</h4>The combined data of prospective registries in Japan, Stroke Acute Management with Urgent Risk-factor Assessment and Improvement-nonvalvular atrial fibrillation (September 2011 to March 2014) and RELAXED (February 2014 to April 2016) were used. Patients were divided into transient ischemic attack and 3 stroke subgroups by the National Institutes of Health Stroke Scale score: mild (0-7), moderate (8-15), and severe (≥16).","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2026-05-31T14:02:00.56Z","creation":"2024-11-19T21:18:33.927Z"},"accession":"S-EPMC9022681","cross_references":{"pubmed":["35105180"],"doi":["10.1161/STROKEAHA.121.036695"]}}