{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ghini V"],"funding":["Regione Toscana"],"pagination":["e1010443"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9022834"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(4)"],"pubmed_abstract":["Metabolomics and lipidomics have been used in several studies to define the biochemical alterations induced by COVID-19 in comparison with healthy controls. Those studies highlighted the presence of a strong signature, attributable to both metabolites and lipoproteins/lipids. Here, 1H NMR spectra were acquired on EDTA-plasma from three groups of subjects: i) hospitalized COVID-19 positive patients (≤21 days from the first positive nasopharyngeal swab); ii) hospitalized COVID-19 positive patients (>21 days from the first positive nasopharyngeal swab); iii) subjects after 2-6 months from SARS-CoV-2 eradication. A Random Forest model built using the EDTA-plasma spectra of COVID-19 patients ≤21 days and Post COVID-19 subjects, provided a high discrimination accuracy (93.6%), indicating both th"],"journal":["PLoS pathogens"],"pubmed_title":["Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients."],"pmcid":["PMC9022834"],"funding_grant_id":["project COMETA, Bando COVID-19"],"pubmed_authors":["Meoni G","Luchinat C","Landini G","Pelagatti L","Ghini V","Celli T","Bertini L","Veneziani F","Petrucci F","Vannucchi V","Turano P"],"additional_accession":[]},"is_claimable":false,"name":"Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients.","description":"Metabolomics and lipidomics have been used in several studies to define the biochemical alterations induced by COVID-19 in comparison with healthy controls. Those studies highlighted the presence of a strong signature, attributable to both metabolites and lipoproteins/lipids. Here, 1H NMR spectra were acquired on EDTA-plasma from three groups of subjects: i) hospitalized COVID-19 positive patients (≤21 days from the first positive nasopharyngeal swab); ii) hospitalized COVID-19 positive patients (>21 days from the first positive nasopharyngeal swab); iii) subjects after 2-6 months from SARS-CoV-2 eradication. A Random Forest model built using the EDTA-plasma spectra of COVID-19 patients ≤21 days and Post COVID-19 subjects, provided a high discrimination accuracy (93.6%), indicating both th","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-19T00:39:37.787Z","creation":"2025-04-07T11:45:44.274Z"},"accession":"S-EPMC9022834","cross_references":{"pubmed":["35446921"],"doi":["10.1371/journal.ppat.1010443"]}}