{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kaze AD"],"funding":["Jackson State University","NIDDK NIH HHS","NHLBI NIH HHS","NIMHD NIH HHS"],"pagination":["e14465"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9023067"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["38(5)"],"pubmed_abstract":["<h4>Aim</h4>To evaluate the association between plasma biomarkers including leptin, adiponectin, adiponectin-to-leptin ratio and high-sensitivity C-reactive protein (hsCRP) with risk of glycaemic progression and incident dysglycaemia (pre-diabetes or diabetes) in a community-based sample of African American (AAs).<h4>Methods</h4>We analysed data from 3223 participants without type 2 diabetes at baseline (2000-2004) who attended ≥1 follow-up visit. Poisson regression was used to generate risk ratios (RRs) for glycaemic progression and incident dysglycaemia.<h4>Results</h4>Over a median of 7 years, 46.4% developed glycaemic progression (n=1495). After adjusting for demographic and lifestyle variables, the RRs (95% CI) for glycaemic progression comparing highest (Q4) to lowest (Q1) quartiles "],"journal":["Diabetic medicine : a journal of the British Diabetic Association"],"pubmed_title":["Plasma adipokines and glycaemic progression among African Americans: Findings from the Jackson Heart Study."],"pmcid":["PMC9023067"],"funding_grant_id":["HHSN268201800015I","HHSN268201800012C","HHSN268201800011C","K23 DK117041","HHSN268201800012I","HHSN268201800011I","HHSN268201800014I","HHSN268201800013I","HHSN268201800010I","HHSN268201800014C"],"pubmed_authors":["Bertoni AG","Ndumele CE","Ahima RS","Echouffo-Tcheugui JB","Musani SK","Golden SH","Correa A","Joseph JJ","Kaze AD","Bidulescu A"],"additional_accession":[]},"is_claimable":false,"name":"Plasma adipokines and glycaemic progression among African Americans: Findings from the Jackson Heart Study.","description":"<h4>Aim</h4>To evaluate the association between plasma biomarkers including leptin, adiponectin, adiponectin-to-leptin ratio and high-sensitivity C-reactive protein (hsCRP) with risk of glycaemic progression and incident dysglycaemia (pre-diabetes or diabetes) in a community-based sample of African American (AAs).<h4>Methods</h4>We analysed data from 3223 participants without type 2 diabetes at baseline (2000-2004) who attended ≥1 follow-up visit. Poisson regression was used to generate risk ratios (RRs) for glycaemic progression and incident dysglycaemia.<h4>Results</h4>Over a median of 7 years, 46.4% developed glycaemic progression (n=1495). After adjusting for demographic and lifestyle variables, the RRs (95% CI) for glycaemic progression comparing highest (Q4) to lowest (Q1) quartiles ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2025-04-25T22:56:21.321Z","creation":"2025-04-06T09:14:35.206Z"},"accession":"S-EPMC9023067","cross_references":{"pubmed":["33236370"],"doi":["10.1111/dme.14465"]}}