biostudies-literatureUnknown13Chen G<h4>Objective</h4>To investigate the correlation between preoperative use of ACEIs/ARBs and postoperative delirium (POD) in surgical patients with pulmonary arterial hypertension (PAH).<h4>Methods</h4>The present study is a secondary analysis of a retrospective cohort study conducted at the University of Washington Medical Center from April 2007 to September 2013. Patients with PAH who underwent non-cardiac, non-obstetric surgery were enrolled in the original research. We further excluded stroke, sepsis, and craniotomy patients from interfering with POD evaluation. The univariate regression analysis and multivariate-adjusted model were used to explore the influence of preoperative ACEIs/ARBs use on the occurrence of POD.<h4>Results</h4>A total of 539 patients were included in this study. TFrontiers in psychiatry851104https://www.ebi.ac.uk/biostudies/studies/S-EPMC9024170biostudies-literatureInfluence of Renin-Angiotensin System Inhibitors on Postoperative Delirium in Patients With Pulmonary Arterial Hypertension: A Secondary Analysis of a Retrospective Cohort Study.PMC9024170Zhou SChen GDeng FfalseInfluence of Renin-Angiotensin System Inhibitors on Postoperative Delirium in Patients With Pulmonary Arterial Hypertension: A Secondary Analysis of a Retrospective Cohort Study.<h4>Objective</h4>To investigate the correlation between preoperative use of ACEIs/ARBs and postoperative delirium (POD) in surgical patients with pulmonary arterial hypertension (PAH).<h4>Methods</h4>The present study is a secondary analysis of a retrospective cohort study conducted at the University of Washington Medical Center from April 2007 to September 2013. Patients with PAH who underwent non-cardiac, non-obstetric surgery were enrolled in the original research. We further excluded stroke, sepsis, and craniotomy patients from interfering with POD evaluation. The univariate regression analysis and multivariate-adjusted model were used to explore the influence of preoperative ACEIs/ARBs use on the occurrence of POD.<h4>Results</h4>A total of 539 patients were included in this study. T2022-01-01T00:00:00Z20222026-04-08T18:11:18.174Z2024-11-20T01:28:15.652ZS-EPMC90241703546353110.3389/fpsyt.2022.851104