{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(4)"],"submitter":["Kita Y"],"pubmed_abstract":["In targeted metabolomic analysis using liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS), hundreds of MRMs are performed in a single run, yielding a large dataset containing thousands of chromatographic peaks. Automation tools for processing large MRM datasets have been reported, but a visual review of chromatograms is still critical, as real samples with biological matrices often cause complex chromatographic patterns owing to non-specific, insufficiently separated, isomeric, and isotopic components. Herein, we report the development of new software, TRACES, a lightweight chromatogram browser for MRM-based targeted LC-MS analysis. TRACES provides rapid access to all MRM chromatograms in a dataset, allowing users to start ad hoc data browsing without preparat"],"journal":["Metabolites"],"pagination":["354"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9027295"],"repository":["biostudies-literature"],"pubmed_title":["TRACES: A Lightweight Browser for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Chromatograms."],"pmcid":["PMC9027295"],"pubmed_authors":["Shimizu T","Tokuoka SM","Kita Y","Oda Y"],"additional_accession":[]},"is_claimable":false,"name":"TRACES: A Lightweight Browser for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Chromatograms.","description":"In targeted metabolomic analysis using liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS), hundreds of MRMs are performed in a single run, yielding a large dataset containing thousands of chromatographic peaks. Automation tools for processing large MRM datasets have been reported, but a visual review of chromatograms is still critical, as real samples with biological matrices often cause complex chromatographic patterns owing to non-specific, insufficiently separated, isomeric, and isotopic components. Herein, we report the development of new software, TRACES, a lightweight chromatogram browser for MRM-based targeted LC-MS analysis. TRACES provides rapid access to all MRM chromatograms in a dataset, allowing users to start ad hoc data browsing without preparat","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-05-18T12:06:47.221Z","creation":"2025-05-18T12:06:47.221Z"},"accession":"S-EPMC9027295","cross_references":{"pubmed":["35448541"],"doi":["10.3390/metabo12040354"]}}