{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Adamoski D"],"funding":["Financiadora de Estudos e Projetos"],"pagination":["809"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9027352"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(4)"],"pubmed_abstract":["Screening efforts and genomic surveillance are essential tools to evaluate the course of the COVID-19 pandemic and assist the public healthcare system in dealing with an increasing number of infections. For the analysis of COVID-19 cases scenarios in Curitiba, Paraná, Brazil, we performed a diagnosis of positive cases, coupled with genotyping, for symptomatic and asymptomatic members of the Federal University of Paraná. We achieved over 1000 samples using RT-qPCR for diagnosis. The posterior genotyping allowed us to observe differences in the spread of strains in Curitiba, Brazil. The Delta variant was not associated with an infection wave, whereas the rapid Omicron variant spread became dominant in less than one month. We also evaluated the general vaccination coverage in the state, obser"],"journal":["Viruses"],"pubmed_title":["SARS-CoV-2 Delta and Omicron Variants Surge in Curitiba, Southern Brazil, and Its Impact on Overall COVID-19 Lethality."],"pmcid":["PMC9027352"],"funding_grant_id":["0494/20"],"pubmed_authors":["Wassem R","Baura VA","Tscha MK","Almeida BMM","Aoki MN","Royer CA","Souza EM","Carvalho de Oliveira J","Rodrigues AC","Gradia DF","Raboni SM","Trindade EDS","Bonatto AC","Nogueira MB","Adamoski D"],"additional_accession":[]},"is_claimable":false,"name":"SARS-CoV-2 Delta and Omicron Variants Surge in Curitiba, Southern Brazil, and Its Impact on Overall COVID-19 Lethality.","description":"Screening efforts and genomic surveillance are essential tools to evaluate the course of the COVID-19 pandemic and assist the public healthcare system in dealing with an increasing number of infections. For the analysis of COVID-19 cases scenarios in Curitiba, Paraná, Brazil, we performed a diagnosis of positive cases, coupled with genotyping, for symptomatic and asymptomatic members of the Federal University of Paraná. We achieved over 1000 samples using RT-qPCR for diagnosis. The posterior genotyping allowed us to observe differences in the spread of strains in Curitiba, Brazil. The Delta variant was not associated with an infection wave, whereas the rapid Omicron variant spread became dominant in less than one month. We also evaluated the general vaccination coverage in the state, obser","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-26T18:31:05.504Z","creation":"2025-02-19T03:28:06.149Z"},"accession":"S-EPMC9027352","cross_references":{"pubmed":["35458539"],"doi":["10.3390/v14040809"]}}