{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Vargas-Alarcon G"],"funding":["Instituto Nacional de Cardiologia Ignacio Chavez"],"pagination":["486"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9027896"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(4)"],"pubmed_abstract":["We conducted a case-control study in order to evaluate whether <i>ABO</i> gene polymorphisms were associated with a high risk of developing COVID-19 in a cohort of patients. Six <i>ABO</i> gene polymorphisms (rs651007 <i>T</i>/<i>C</i>, rs579459 <i>T</i>/<i>C</i>, rs495828 <i>T/G</i>, rs8176746 <i>A/C</i>, rs8176740 <i>T/A</i>, and rs512770 <i>T</i>/<i>C</i>) were determined using TaqMan genotyping assays in a group of 415 COVID-19 patients and 288 healthy controls. The distribution of rs651007 <i>T</i>/<i>C</i>, rs579459 <i>T</i>/<i>C</i>, rs495828 <i>T</i>/<i>G</i>, and rs8176746 <i>A</i>/<i>C</i> polymorphisms was similar in patients and healthy controls. Nonetheless, under co-dominant (OR = 1.89, pC<sub>Co-dominant</sub> = 6 × 10<sup>-6</sup>), recessive (OR = 1.98, pC<sub>Recessive</s"],"journal":["Biomolecules"],"pubmed_title":["The rs8176740 <i>T/A</i> and rs512770 <i>T/C</i> Genetic Variants of the <i>ABO</i> Gene Increased the Risk of COVID-19, as well as the Plasma Concentration Platelets."],"pmcid":["PMC9027896"],"funding_grant_id":["Project-21-1237"],"pubmed_authors":["Ramirez-Bello J","Posadas-Sanchez R","Rojas-Velasco G","Ortega-Pena S","Arellano-Gonzalez M","Fragoso JM","Montufar-Robles I","Vargas-Alarcon G","Lopez-Reyes A","Martinez-Gomez L","Barbosa-Cobos RE"],"additional_accession":[]},"is_claimable":false,"name":"The rs8176740 <i>T/A</i> and rs512770 <i>T/C</i> Genetic Variants of the <i>ABO</i> Gene Increased the Risk of COVID-19, as well as the Plasma Concentration Platelets.","description":"We conducted a case-control study in order to evaluate whether <i>ABO</i> gene polymorphisms were associated with a high risk of developing COVID-19 in a cohort of patients. Six <i>ABO</i> gene polymorphisms (rs651007 <i>T</i>/<i>C</i>, rs579459 <i>T</i>/<i>C</i>, rs495828 <i>T/G</i>, rs8176746 <i>A/C</i>, rs8176740 <i>T/A</i>, and rs512770 <i>T</i>/<i>C</i>) were determined using TaqMan genotyping assays in a group of 415 COVID-19 patients and 288 healthy controls. The distribution of rs651007 <i>T</i>/<i>C</i>, rs579459 <i>T</i>/<i>C</i>, rs495828 <i>T</i>/<i>G</i>, and rs8176746 <i>A</i>/<i>C</i> polymorphisms was similar in patients and healthy controls. Nonetheless, under co-dominant (OR = 1.89, pC<sub>Co-dominant</sub> = 6 × 10<sup>-6</sup>), recessive (OR = 1.98, pC<sub>Recessive</s","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-06-01T00:50:50.943Z","creation":"2024-11-13T11:05:35.397Z"},"accession":"S-EPMC9027896","cross_references":{"pubmed":["35454075"],"doi":["10.3390/biom12040486"]}}