biostudies-literatureUnknown19(8)Makowska KBisphenol A (BPA) is an organic substance widely used in the plastics industry. It penetrates food and environment and, as an endocrine disruptor, has detrimental effects on human organisms. Pet animals, which live in the immediate vicinity of humans, are also exposed to BPA; however, knowledge regarding the exposure of dogs to this substance is extremely scarce. This is the first study in which hair analysis has been used to biomonitor BPA in 30 dogs using liquid chromatography and tandem mass spectrometry techniques. The presence of BPA in concentration levels above the method detection limit (1.25 ng/g) was noted in 93.33% of samples. BPA concentration levels were found to range from 7.05 ng/g to 436 ng/g (mean 81.30 ng/g). Statistically significant differences in BPA concentration leveInternational journal of environmental research and public health4600https://www.ebi.ac.uk/biostudies/studies/S-EPMC9030106biostudies-literatureHair Sample Analysis as a Method of Monitoring Exposure to Bisphenol A in Dogs.PMC9030106Alonso EGonkowski SMartin JAparicio IMakowska KSantos JLRychlik AfalseHair Sample Analysis as a Method of Monitoring Exposure to Bisphenol A in Dogs.Bisphenol A (BPA) is an organic substance widely used in the plastics industry. It penetrates food and environment and, as an endocrine disruptor, has detrimental effects on human organisms. Pet animals, which live in the immediate vicinity of humans, are also exposed to BPA; however, knowledge regarding the exposure of dogs to this substance is extremely scarce. This is the first study in which hair analysis has been used to biomonitor BPA in 30 dogs using liquid chromatography and tandem mass spectrometry techniques. The presence of BPA in concentration levels above the method detection limit (1.25 ng/g) was noted in 93.33% of samples. BPA concentration levels were found to range from 7.05 ng/g to 436 ng/g (mean 81.30 ng/g). Statistically significant differences in BPA concentration leve2022-01-01T00:00:00Z2022 Apr2025-06-01T12:11:03.167Z2025-06-01T12:11:03.167ZS-EPMC90301063545746310.3390/ijerph19084600