{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(32)"],"submitter":["Zhang T"],"pubmed_abstract":["Synthetic methods for the preparation of thioketals featuring CF<sub>3</sub> groups are rare. Here, we have developed a copper-catalyzed thioketalization of enones bearing CF<sub>3</sub> groups and various mercaptans. 24 thioketal molecules have been obtained with moderate to excellent yield. Meanwhile, a preparative scale experiment has been performed giving over 95% yield. This work allows the straightforward formation of thioketals containing CF<sub>3</sub> groups and unsaturated double bonds."],"journal":["RSC advances"],"pagination":["19832-19835"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9033665"],"repository":["biostudies-literature"],"pubmed_title":["Copper-catalyzed thioketalization of enones featuring trifluoromethyl groups."],"pmcid":["PMC9033665"],"pubmed_authors":["Zhang T","Gao Z"],"additional_accession":[]},"is_claimable":false,"name":"Copper-catalyzed thioketalization of enones featuring trifluoromethyl groups.","description":"Synthetic methods for the preparation of thioketals featuring CF<sub>3</sub> groups are rare. Here, we have developed a copper-catalyzed thioketalization of enones bearing CF<sub>3</sub> groups and various mercaptans. 24 thioketal molecules have been obtained with moderate to excellent yield. Meanwhile, a preparative scale experiment has been performed giving over 95% yield. This work allows the straightforward formation of thioketals containing CF<sub>3</sub> groups and unsaturated double bonds.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2025-04-25T22:56:43.973Z","creation":"2025-04-06T09:14:16.664Z"},"accession":"S-EPMC9033665","cross_references":{"pubmed":["35479255"],"doi":["10.1039/d1ra03222d"]}}