{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Wan-Tong Z"],"funding":["National Natural Science Foundation of China"],"pubmed_abstract":["<b>Background:</b> No effective medication is available for symptomatic bradyarrhythmia, particularly in low socioeconomic status (SES) population. <b>Objective:</b> To explore the safety and efficacy of Yuanjiang decoction, a traditional Chinese medicinal prescription, for symptomatic bradyarrhythmia on a compassionate-use basis. <b>Methods:</b> This compassionate-use study was conducted in Beijing, China between January 2019 and January 2020. Eligible participants were recruited and treated with Yuanjiang decoction (composed of 6 Chinese herbal medicines), 200 ml twice daily for 16 weeks. Analyses were done with the intention-to-treat (ITT) approach. The primary outcome measure was the proportion of participants who achieved a favorable treatment outcome at 16 weeks. <b>Results:</b> As o"],"journal":["Frontiers in pharmacology"],"pagination":["764930"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9035522"],"repository":["biostudies-literature"],"pubmed_title":["Compassionate Use of Yuanjiang Decoction, a Traditional Chinese Medicinal Prescription, for Symptomatic Bradyarrhythmia."],"pmcid":["PMC9035522"],"pubmed_authors":["Bao-Chen Z","Miles P","Zhao L","Xu-Jie W","Wan-Tong Z","Yu-Fei W","Wei T","Rui G","Ning X","Wei-Liang W","Qiu-Yan L","Hao-Xiang L"],"additional_accession":[]},"is_claimable":false,"name":"Compassionate Use of Yuanjiang Decoction, a Traditional Chinese Medicinal Prescription, for Symptomatic Bradyarrhythmia.","description":"<b>Background:</b> No effective medication is available for symptomatic bradyarrhythmia, particularly in low socioeconomic status (SES) population. <b>Objective:</b> To explore the safety and efficacy of Yuanjiang decoction, a traditional Chinese medicinal prescription, for symptomatic bradyarrhythmia on a compassionate-use basis. <b>Methods:</b> This compassionate-use study was conducted in Beijing, China between January 2019 and January 2020. Eligible participants were recruited and treated with Yuanjiang decoction (composed of 6 Chinese herbal medicines), 200 ml twice daily for 16 weeks. Analyses were done with the intention-to-treat (ITT) approach. The primary outcome measure was the proportion of participants who achieved a favorable treatment outcome at 16 weeks. <b>Results:</b> As o","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-21T16:47:09.495Z","creation":"2025-04-21T16:47:09.495Z"},"accession":"S-EPMC9035522","cross_references":{"pubmed":["35479315"],"doi":["10.3389/fphar.2022.764930"]}}