{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(20)"],"submitter":["Zhang S"],"pubmed_abstract":["Zinc finger antiviral proteins (ZAP) can significantly inhibit the replication of avian leukosis virus subgroup J (ALV-J), but the traditional method of ZAP administration is by injection, which can easily cause stress effects in chickens. In this work, we established a sodium alginate/atractylodis macrocephalae system for the encapsulation of CCCH-type zinc finger antiviral protein (CCCH-ZAP). Because of the high cost of ZAP, we first chose bovine serum albumin (BSA) as a model protein to investigate the encapsulation performance. The SEM images clearly confirmed that BSA and the sodium alginate/atractylodis macrocephalae system can assemble easily to form relatively stable nanostructures, and the encapsulation amount of BSA can reach 68%. Subsequently, the encapsulation of ZAP was studie"],"journal":["RSC advances"],"pagination":["12600-12606"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9040642"],"repository":["biostudies-literature"],"pubmed_title":["Assembly encapsulation of BSA and CCCH-ZAP in the sodium alginate/atractylodis macrocephalae system."],"pmcid":["PMC9040642"],"pubmed_authors":["Li Y","Fan H","Yang K","Yi C","Liu S","Zhang S","Sun J","Cheng Z"],"additional_accession":[]},"is_claimable":false,"name":"Assembly encapsulation of BSA and CCCH-ZAP in the sodium alginate/atractylodis macrocephalae system.","description":"Zinc finger antiviral proteins (ZAP) can significantly inhibit the replication of avian leukosis virus subgroup J (ALV-J), but the traditional method of ZAP administration is by injection, which can easily cause stress effects in chickens. In this work, we established a sodium alginate/atractylodis macrocephalae system for the encapsulation of CCCH-type zinc finger antiviral protein (CCCH-ZAP). Because of the high cost of ZAP, we first chose bovine serum albumin (BSA) as a model protein to investigate the encapsulation performance. The SEM images clearly confirmed that BSA and the sodium alginate/atractylodis macrocephalae system can assemble easily to form relatively stable nanostructures, and the encapsulation amount of BSA can reach 68%. Subsequently, the encapsulation of ZAP was studie","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-22T07:50:00.604Z","creation":"2025-04-05T22:16:46.727Z"},"accession":"S-EPMC9040642","cross_references":{"pubmed":["35480363"],"doi":["10.1039/d2ra01767a"]}}