{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(2)"],"submitter":["Barbosa da Costa N"],"funding":["Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada","Canada Research Chairs"],"pubmed_abstract":["Agrochemicals often contaminate freshwater bodies, affecting microbial communities that underlie aquatic food webs. For example, the herbicide glyphosate has the potential to indirectly select for antibiotic-resistant bacteria. Such cross-selection could occur if the same genes (encoding efflux pumps, for example) confer resistance to both glyphosate and antibiotics. To test for cross-resistance in natural aquatic bacterial communities, we added a glyphosate-based herbicide (GBH) to 1,000-liter mesocosms filled with water from a pristine lake. Over 57 days, we tracked changes in bacterial communities with shotgun metagenomic sequencing and annotated metagenome-assembled genomes (MAGs) for the presence of known antibiotic resistance genes (ARGs), plasmids, and resistance mutations in the en"],"journal":["mSystems"],"pagination":["e0148221"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9040730"],"repository":["biostudies-literature"],"pubmed_title":["A Glyphosate-Based Herbicide Cross-Selects for Antibiotic Resistance Genes in Bacterioplankton Communities."],"pmcid":["PMC9040730"],"pubmed_authors":["Fussmann GF","Barbosa da Costa N","Fugere V","Shapiro BJ","Terrat Y","Hebert MP","Gonzalez A"],"additional_accession":[]},"is_claimable":false,"name":"A Glyphosate-Based Herbicide Cross-Selects for Antibiotic Resistance Genes in Bacterioplankton Communities.","description":"Agrochemicals often contaminate freshwater bodies, affecting microbial communities that underlie aquatic food webs. For example, the herbicide glyphosate has the potential to indirectly select for antibiotic-resistant bacteria. Such cross-selection could occur if the same genes (encoding efflux pumps, for example) confer resistance to both glyphosate and antibiotics. To test for cross-resistance in natural aquatic bacterial communities, we added a glyphosate-based herbicide (GBH) to 1,000-liter mesocosms filled with water from a pristine lake. Over 57 days, we tracked changes in bacterial communities with shotgun metagenomic sequencing and annotated metagenome-assembled genomes (MAGs) for the presence of known antibiotic resistance genes (ARGs), plasmids, and resistance mutations in the en","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-06-07T03:18:40.365Z","creation":"2025-04-20T03:07:51.569Z"},"accession":"S-EPMC9040730","cross_references":{"pubmed":["35266795"],"doi":["10.1128/msystems.01482-21"]}}