biostudies-literatureCheedarala RKNational Research Foundation of Korea32942-32954https://www.ebi.ac.uk/biostudies/studies/S-EPMC9042156biostudies-literatureUnknown11(52)We have reported an aerobic oxidation of primary and secondary alcohols to respective aldehydes and ketones using a bipyridyl-cinchona alkaloid based palladium catalytic system (PdAc-5) using oxygen at moderate pressure. The PdAc-5 catalyst was analysed using SEM, EDAX, and XPS analysis. The above catalytic system is used in experiments for different oxidation systems which include different solvents, additives, and bases which are cheap, robust, non-toxic, and commercially available on the industrial bench. The obtained products are quite appreciable in both yield and selectivity (70-85%). In addition, numerous important studies, such as comparisons with various commercial catalysts, solvent systems, mixture of solvents, and catalyst mole%, were conducted using PdAc-5. The synthetic stratRSC advancesAn aerobic oxidation of alcohols into carbonyl synthons using bipyridyl-cinchona based palladium catalyst.PMC90421562019R1A2C10111132018R1A6A1A030245092017R1A2B2011730Cheedarala RKSiva ASong JIChidambaram RRfalseAn aerobic oxidation of alcohols into carbonyl synthons using bipyridyl-cinchona based palladium catalyst.We have reported an aerobic oxidation of primary and secondary alcohols to respective aldehydes and ketones using a bipyridyl-cinchona alkaloid based palladium catalytic system (PdAc-5) using oxygen at moderate pressure. The PdAc-5 catalyst was analysed using SEM, EDAX, and XPS analysis. The above catalytic system is used in experiments for different oxidation systems which include different solvents, additives, and bases which are cheap, robust, non-toxic, and commercially available on the industrial bench. The obtained products are quite appreciable in both yield and selectivity (70-85%). In addition, numerous important studies, such as comparisons with various commercial catalysts, solvent systems, mixture of solvents, and catalyst mole%, were conducted using PdAc-5. The synthetic strat2021-01-01T00:00:00Z2021 Oct2025-04-19T12:58:43.827Z2025-04-19T12:58:43.827ZS-EPMC90421563549360510.1039/d1ra05855j