{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Al-Enezi MY"],"funding":["Kuwait University"],"pagination":["37866-37876"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9044017"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(60)"],"pubmed_abstract":["Three novel phosphine-free Ru-alkylidenes (7a-7c) have been synthesized and utilized as efficient catalysts for ring closing metathesis (RCM) reaction. Spectroscopic data, <i>i.e.</i> NMR and HRMS, along with single crystal X-ray diffraction analysis, were used to confirm their chemical structures. The tosylated carbenoid 7b showed the highest efficiency in cyclizing different acyclic diene substrates. RCM of various (un)substituted <i>N</i>,<i>N</i>-diallylaniline derivatives and stereoselective RCM of different macromolecular dienes were well tolerated using only a catalytic amount (0.5-2.0 mol%) of the additive catalyst (7b) as compared to the well-known Grubbs (II) and Hoveyda-Grubbs (II) catalysts."],"journal":["RSC advances"],"pubmed_title":["Highly efficient Ru(ii)-alkylidene based Hoveyda-Grubbs catalysts for ring-closing metathesis reactions."],"pmcid":["PMC9044017"],"funding_grant_id":["SC 11/16"],"pubmed_authors":["John E","Ibrahim YA","Al-Enezi MY","Al-Awadi NA"],"additional_accession":[]},"is_claimable":false,"name":"Highly efficient Ru(ii)-alkylidene based Hoveyda-Grubbs catalysts for ring-closing metathesis reactions.","description":"Three novel phosphine-free Ru-alkylidenes (7a-7c) have been synthesized and utilized as efficient catalysts for ring closing metathesis (RCM) reaction. Spectroscopic data, <i>i.e.</i> NMR and HRMS, along with single crystal X-ray diffraction analysis, were used to confirm their chemical structures. The tosylated carbenoid 7b showed the highest efficiency in cyclizing different acyclic diene substrates. RCM of various (un)substituted <i>N</i>,<i>N</i>-diallylaniline derivatives and stereoselective RCM of different macromolecular dienes were well tolerated using only a catalytic amount (0.5-2.0 mol%) of the additive catalyst (7b) as compared to the well-known Grubbs (II) and Hoveyda-Grubbs (II) catalysts.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-05T14:42:55.888Z","creation":"2025-04-05T14:42:55.888Z"},"accession":"S-EPMC9044017","cross_references":{"pubmed":["35498076"],"doi":["10.1039/d1ra07428h"]}}