{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(62)"],"submitter":["Ramazanov IR"],"pubmed_abstract":["The reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp<sub>2</sub>ZrCl<sub>2</sub> and 1 equivalent of Et<sub>3</sub>Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield. Trimethylsilyl-substituted α,ω-diynes react with the Cp<sub>2</sub>ZrCl<sub>2</sub> - Et<sub>3</sub>Al reagent system to give (1<i>Z</i>,2<i>Z</i>)-1,2-bis(iodo(trimethylsilyl)methylene)cycloalkanes after iodinolysis."],"journal":["RSC advances"],"pagination":["39518-39522"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9044544"],"repository":["biostudies-literature"],"pubmed_title":["Cp<sub>2</sub>ZrCl<sub>2</sub> - Et<sub>3</sub>Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes."],"pmcid":["PMC9044544"],"pubmed_authors":["Amirova AK","Mozgovoj OS","Dzhemilev UM","Kadikova RN","Ramazanov IR"],"additional_accession":[]},"is_claimable":false,"name":"Cp<sub>2</sub>ZrCl<sub>2</sub> - Et<sub>3</sub>Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes.","description":"The reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp<sub>2</sub>ZrCl<sub>2</sub> and 1 equivalent of Et<sub>3</sub>Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield. Trimethylsilyl-substituted α,ω-diynes react with the Cp<sub>2</sub>ZrCl<sub>2</sub> - Et<sub>3</sub>Al reagent system to give (1<i>Z</i>,2<i>Z</i>)-1,2-bis(iodo(trimethylsilyl)methylene)cycloalkanes after iodinolysis.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-26T15:16:27.291Z","creation":"2025-04-06T14:52:39.993Z"},"accession":"S-EPMC9044544","cross_references":{"pubmed":["35492468"],"doi":["10.1039/d1ra08268j"]}}