biostudies-literatureUnknown11(62)Ramazanov IRThe reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp<sub>2</sub>ZrCl<sub>2</sub> and 1 equivalent of Et<sub>3</sub>Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield. Trimethylsilyl-substituted α,ω-diynes react with the Cp<sub>2</sub>ZrCl<sub>2</sub> - Et<sub>3</sub>Al reagent system to give (1<i>Z</i>,2<i>Z</i>)-1,2-bis(iodo(trimethylsilyl)methylene)cycloalkanes after iodinolysis.RSC advances39518-39522https://www.ebi.ac.uk/biostudies/studies/S-EPMC9044544biostudies-literatureCp<sub>2</sub>ZrCl<sub>2</sub> - Et<sub>3</sub>Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes.PMC9044544Amirova AKMozgovoj OSDzhemilev UMKadikova RNRamazanov IRfalseCp<sub>2</sub>ZrCl<sub>2</sub> - Et<sub>3</sub>Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes.The reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp<sub>2</sub>ZrCl<sub>2</sub> and 1 equivalent of Et<sub>3</sub>Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield. Trimethylsilyl-substituted α,ω-diynes react with the Cp<sub>2</sub>ZrCl<sub>2</sub> - Et<sub>3</sub>Al reagent system to give (1<i>Z</i>,2<i>Z</i>)-1,2-bis(iodo(trimethylsilyl)methylene)cycloalkanes after iodinolysis.2021-01-01T00:00:00Z2021 Dec2025-04-26T15:16:27.291Z2025-04-06T14:52:39.993ZS-EPMC90445443549246810.1039/d1ra08268j