{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rogers M"],"funding":["National Health and Medical Research Council"],"pagination":["e060520"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9045043"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(4)"],"pubmed_abstract":["Introduction
Shift workers are at an increased risk of developing obesity and type 2 diabetes. Eating and sleeping out of synchronisation with endogenous circadian rhythms causes weight gain, hyperglycaemia and insulin resistance. Interventions that promote weight loss and reduce the metabolic consequences of eating at night are needed for night shift workers. The aim of this study is to examine the effects of three weight loss strategies on weight loss and insulin resistance (HOMA-IR) in night shift workers.Methods and analysis
A multisite 18-month, three-arm randomised controlled trial comparing three weight loss strategies; continuous energy restriction; and two intermittent fasting strategies whereby participants will fast for 2 days per week (5:2); either during the da"],"journal":["BMJ open"],"pubmed_title":["Study protocol for the Shifting Weight using Intermittent Fasting in night shift workers (SWIFt) study: a three-arm randomised controlled trial comparing three weight loss strategies in night shift workers with obesity."],"pmcid":["PMC9045043"],"funding_grant_id":["APP1159762"],"pubmed_authors":["Dorrian J","Bonham MP","Davis R","Banks S","Sletten TL","Coates A","Yates CL","Rogers M","Huggins CE","Davis C","Phoi YY","Kellow NJ","Leung GK","Clark AB","Iacovou M"],"additional_accession":[]},"is_claimable":false,"name":"Study protocol for the Shifting Weight using Intermittent Fasting in night shift workers (SWIFt) study: a three-arm randomised controlled trial comparing three weight loss strategies in night shift workers with obesity.","description":"Introduction
Shift workers are at an increased risk of developing obesity and type 2 diabetes. Eating and sleeping out of synchronisation with endogenous circadian rhythms causes weight gain, hyperglycaemia and insulin resistance. Interventions that promote weight loss and reduce the metabolic consequences of eating at night are needed for night shift workers. The aim of this study is to examine the effects of three weight loss strategies on weight loss and insulin resistance (HOMA-IR) in night shift workers.Methods and analysis
A multisite 18-month, three-arm randomised controlled trial comparing three weight loss strategies; continuous energy restriction; and two intermittent fasting strategies whereby participants will fast for 2 days per week (5:2); either during the da","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-04T23:34:28.816Z","creation":"2025-04-04T23:34:28.816Z"},"accession":"S-EPMC9045043","cross_references":{"pubmed":["35473743"],"doi":["10.1136/bmjopen-2021-060520"]}}