{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wu J"],"funding":["Strategic Priority Research Program of the Chinese Academy of Science","National Natural Science Foundation of China"],"pagination":["e0254521"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9045151"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(2)"],"pubmed_abstract":["Feeding a growing global population and lowering environmental pollution are the two biggest challenges facing ruminant livestock. Considering the significance of nitrogen metabolism in these challenges, a dietary intervention regarding metabolizable protein profiles with different rumen-undegradable protein (RUP) ratios (high RUP [HRUP] versus low RUP [LRUP]) was conducted in young ruminants with weaned goats as a model. Fecal samples were collected longitudinally for nine consecutive weeks to dissect the timing and duration of intervention, as well as its mechanism of action involving the gut microbiota. Results showed that at least 6 weeks of intervention were needed to distinguish the beneficial effects of HRUP, and HRUP intervention improved the metabolic efficiency of goats as eviden"],"journal":["Microbiology spectrum"],"pubmed_title":["Enhancing Metabolic Efficiency through Optimizing Metabolizable Protein Profile in a Time Progressive Manner with Weaned Goats as a Model: Involvement of Gut Microbiota."],"pmcid":["PMC9045151"],"funding_grant_id":["U20A2057","XDA26040304","31730092"],"pubmed_authors":["Wang M","Wu J","Zhou C","Tan Z","Zhang X","Jiao J"],"additional_accession":[]},"is_claimable":false,"name":"Enhancing Metabolic Efficiency through Optimizing Metabolizable Protein Profile in a Time Progressive Manner with Weaned Goats as a Model: Involvement of Gut Microbiota.","description":"Feeding a growing global population and lowering environmental pollution are the two biggest challenges facing ruminant livestock. Considering the significance of nitrogen metabolism in these challenges, a dietary intervention regarding metabolizable protein profiles with different rumen-undegradable protein (RUP) ratios (high RUP [HRUP] versus low RUP [LRUP]) was conducted in young ruminants with weaned goats as a model. Fecal samples were collected longitudinally for nine consecutive weeks to dissect the timing and duration of intervention, as well as its mechanism of action involving the gut microbiota. Results showed that at least 6 weeks of intervention were needed to distinguish the beneficial effects of HRUP, and HRUP intervention improved the metabolic efficiency of goats as eviden","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-05-09T23:40:55.807Z","creation":"2025-04-04T19:32:30.637Z"},"accession":"S-EPMC9045151","cross_references":{"pubmed":["35416718"],"doi":["10.1128/spectrum.02545-21"]}}